Propagating neuronal discharges in neocortical slices: computational and experimental study

D Golomb, Y Amitai - Journal of neurophysiology, 1997 - journals.physiology.org
Golomb, David and Yael Amitai. Propagating neuronal discharges in neocortical slices:
computational and experimental study. J. Neurophysiol. 78: 1199–1211, 1997. We studied …

Segregation of seizures and spreading depolarization across cortical layers

A Zakharov, K Chernova, G Burkhanova… - …, 2019 - Wiley Online Library
Objective Cortical spreading depolarization (SD) and seizures are often co‐occurring
electrophysiological phenomena. However, the cross‐layer dynamics of SD during seizures …

Metabotropic glutamate receptor activation modulates epileptiform activity in the hippocampus

PA Rutecki, Y Yang - Neuroscience, 1997 - Elsevier
Synchronous neuronal activity that resembles interictal epileptiform discharges occurs in
hippocampal slices if there is an imbalance of inhibitory and excitatory synaptic activity …

Dynamics of evoked local field potentials in the hippocampus of epileptic rats with spontaneous seizures

CM Queiroz, JA Gorter… - Journal of …, 2009 - journals.physiology.org
A change in neuronal network excitability within the hippocampus is one of the hallmarks of
temporal lobe epilepsy (TLE). In the dentate gyrus (DG), however, neuronal loss and mossy …

Imaging the induction and spread of seizure activity in the isolated brain of the guinea pig: the roles of GABA and glutamate receptors

P Federico, BA MAcVICAR - Journal of neurophysiology, 1996 - journals.physiology.org
1. The induction and spread of seizure activity was studied using imaging and
electrophysiological techniques in the isolated whole brain of the guinea pig. We examined …

Spread of low Mg2+ induced epileptiform activity from the rat entorhinal cortex to the hippocampus after kindling studied in vitro

J Behr, T Gloveli, R Gutierrez, U Heinemann - Neuroscience letters, 1996 - Elsevier
Extracellular recordings were performed in in vitro combined hippocampal-entorhinal cortex
(HC-EC) slices obtained from control and amygdala kindled rats to investigate the spread of …

Laminar cortical interactions during epileptic spikes studied with principal component analysis and physiological modeling

DS Barth, S Di, C Baumgartner - Brain research, 1989 - Elsevier
The direct cortical responses (DCR) to electrical stimulation and electrically evoked interictal
penicillin spikes (EIIS) were studied in the same rats using current source-density (CSD) …

[HTML][HTML] Effects of anti-epileptic drugs on spreading depolarization-induced epileptiform activity in mouse hippocampal slices

CH Lin, SP Hsu, TC Cheng, CW Huang, YC Chiang… - Scientific reports, 2017 - nature.com
Epilepsy and spreading depolarization (SD) are both episodic brain disorders and often
exist together in the same individual. In CA1 pyramidal neurons of mouse hippocampal …

Models of the cellular mechanism underlying propagation of epileptiform activity in the CA2-CA3 region of the hippocampal slice

RD Traub, WD Knowles, R Miles, RKS Wong - Neuroscience, 1987 - Elsevier
We have shown experimentally in theprevious paper that spontaneous epileptiform activity,
as recorded by extracellular field potentials, propagates smoothly across the CA2-CA3 …

Independent epileptiform discharge patterns in the olfactory and limbic areas of the in vitro isolated Guinea pig brain during 4-aminopyridine treatment

G Carriero, L Uva, V Gnatkovsky… - Journal of …, 2010 - journals.physiology.org
In vitro studies performed on brain slices demonstrate that the potassium channel blocker 4-
aminopyridine (4AP, 50 μM) discloses electrographic seizure activity and interictal …