Ionotropic glutamate and GABA receptors in human epileptic neocortical tissue: quantitative in vitro receptor autoradiography

K Zilles, MS Qü, R Köhling, EJ Speckmann - Neuroscience, 1999 - Elsevier
Since a disturbed balance between excitatory and inhibitory amino acid receptors is
suggested to be an important condition for epileptogenic cortical activity, the present study …

Excitatory and inhibitory control of epileptiform discharges in combined hippocampal/entorhinal cortical slices

LM de la Prida, MA Pozo - Brain research, 2002 - Elsevier
We examined whether epileptiform activity can be induced and prevented by mild reduction
of GABAA receptor-mediated inhibition and non-NMDA receptor-mediated excitation …

Regional forebrain noradrenalin release in response to focal and generalized seizures induced by hippocampal kindling stimulation

J Bengzon, I Kikvadze, M Kokaia… - European Journal of …, 1992 - Wiley Online Library
In vivo microdialysis was used to monitor noradrenalin (NA) release in the rat hippocampus,
sensorimotor cortex and amygdala in response to seizures induced by electrical kindling …

Glutamate currents in morphologically identified human dentate granule cells in temporal lobe epilepsy

M Isokawa, M Levesque, I Fried… - Journal of …, 1997 - journals.physiology.org
Isokawa, Masako, Michel Levesque, Itzhak Fried, and Jerome Engel, Jr. Glutamate currents
in morphologically identified human dentate granule cells in temporal lobe epilepsy. J …

Spreading depression enhances the spontaneous epileptiform activity in human neocortical tissues

A Gorji, EJ Speckmann - European Journal of Neuroscience, 2004 - Wiley Online Library
Spreading depression (SD) is a well‐known phenomenon in animal models of experimental
epilepsy. However, the interaction of SD with epileptiform activity in human neuronal tissues …

[HTML][HTML] Evoked epileptiform discharges in the rat anterior piriform cortex: generation and local propagation

J Doherty, K Gale, DA Eagles - Brain research, 2000 - Elsevier
The purpose of this study was to identify cellular and synaptic properties of neurons in a
small region within the anterior piriform cortex (aPC), termed the area tempestas (AT) …

Induction of delayed synchronized bursts in hippocampal slices by weak sine-wave stimulation; role of the NMDA receptor

SM Bawin, I Shahhal, MD Mahoney, WR Adey - Epilepsy research, 1989 - Elsevier
Abstract Weak (20–50 μA) sine-wave stimulation at 60 Hz (SWS) of either the mossy fibers
or the Schaffer collaterals promoted epileptiform synchronized bursts in the CA2/3 area of rat …

Epileptiform burst responses in ventral vs dorsal hippocampal slices

M Gilbert, RJ Racine, GK Smith - Brain research, 1985 - Elsevier
Field potentials from area CA1 evoked by stimulation of the Schaffer collaterals were
compared in dorsal and ventral hippocampal slices of rat brain. Responses were …

[引用][C] Distant effects of a focal epileptogenic process

RM Crowell - Brain Research, 1970 - Elsevier
Epileptiform activity originating from a discrete epileptogenic cortical focus may give rise to
concomitant'projected discharges' in distant regions of the brain which are synaptically …

Effects of antiepileptic drugs on afterdischarge generation in rat hippocampal slices

K Ohno, M Higashima - Brain research, 2002 - Elsevier
We have recently reported that ictal-like afterdischarges (ADs) analogous to those in in vivo
kindling models are induced by high-frequency stimulation (100 Hz, 1s) to the stratum …