Cervical cancer is one of the most important cause of cancer-related death and presents a
major public health problem in many countries. To search for more novel antitumor agents …

Nineteen erlotinib derivatives bearing different 1, 2, 3-triazole moieties were designed,
synthesized, and evaluated for their potential against different cancer cell lines. The …

Herein, we synthesized some new indole-1, 3, 4-oxadiazole based sulfonyl 1, 2, 3-triazoles
via a click chemistry approach and then characterized their structures by NMR, mass, and …

Abstract A series of 1, 3, 4‐oxadiazole‐1, 2, 3‐triazole hybrids bearing different
pharmacophoric moieties has been designed and synthesized. Their antiproliferative activity …

Chemotherapy is an indispensable tool to treat cancer, therefore, the development of new
drugs that can treat cancer with minimal side effects and lead to more favorable prognoses …

Herein, we prepared some new imidazole-1, 2, 4-oxadiazole hybrids (6a–6o) and
investigated their antiproliferative potential on three human cancer cell lines (HepG2, A549 …

The synthesis of some novel 4‐azaindole‐1, 2, 4‐oxadiazole hybrids (5 a–5 q) from the
reaction between 1H‐pyrrolo [3, 2‐b] pyridine‐3‐carbonitrile and readily available aromatic …

We herein report the design and synthesis of new 1, 3, 5-triazine-based pyrazole derivatives
(5a–i) with anticancer activity targeting the epidermal growth factor (EGFR) tyrosine kinase …

2, 3, 4-trisubstituted thiazoles 3a–i, having a methyl group in position four, were synthesized
by the reaction of 1, 4-disubstituted thiosemicarbazides with chloroacetone in ethyl …

Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2) are crucial
targetable enzymes in cancer management. Therefore, herein, new 2-[(5-((1 H-indol-3-yl) …