In the current study, we report the synthesis and cytotoxic evaluation of a new series of S-
benzo [4, 5] thiazolo [2, 3-c][1, 2, 4] triazole-based derivatives 8-12. Cytotoxicity of the new …

Several hybrid molecules of diphenylamine-2, 4-dicarboxamide with various azolidinones
and related heterocyclic rings have been synthesized and explored as epidermal growth …

Abstract New quinoxaline‐sulfonyl‐1, 2, 4‐triazole hybrids were synthesized (5 a–n) via
systematic step‐wise sequence. Later, the in vitro cytotoxicity screening of all these …

The current study focuses on developing a single molecule that acts as an antiproliferative
agent with dual or multi-targeted action, reducing drug resistance and adverse effects. A …

Introduction: Cancer is reported to be one of the most life-threatening diseases. Major
limitations of currently used anticancer agents are drug resistance, very small therapeutic …

A diverse series of 22 indolyl‐1, 2, 4‐triazole congeners (6 and 7) have been synthesized
from the reaction of indole‐3‐carbonitrile (4) or (5) with appropriate acid hydrazides in the …

In search of the new anticancer agents, a series of novel new 5-aryl-3-((quinolin-8-
ylsulfonyl) methyl)-1, 2, 4-oxadiazole derivatives were synthesized using 2-(quinolin-8 …

EGFR and VEGFR-2 represent promising targets for cancer treatment as they are very
important in tumor development as well as in angiogenesis and metastasis. In this work, 6 …

EGFR (epidermal growth factor receptor) tyrosine kinases are frequently used in recent
years, especially in small cell lung cancer. As with all other anticancer drugs, problems such …

A series of compounds which contain pyrazole, thiazole and naphthalene ring (1a–7a, 1b–
7b, 1c–7c, 1d–7d) were firstly synthesized and their anti-proliferative activity, EGFR …