Aquaporins (AQPs) represent a diverse family of membrane proteins found in prokaryotes
and eukaryotes. The primary aquaporins expressed in the mammalian brain are AQP1 …

Water homeostasis in the brain is of central physiologic and clinical importance. Neuronal
activity and ion water homeostasis are inextricably coupled. For example, the clearance of …

The aquaporins (AQPs) are plasma membrane water-transporting proteins. AQP4 is the
principal member of this protein family in the CNS, where it is expressed in astrocytes and is …

Aquaporins (AQPs), integral membrane proteins facilitating selective water and solute
transport across cell membranes, have been the focus of extensive research over the past …

Six years have elapsed since the publication of the Neuroscience Special Issue entitled
“Brain Water Homeostasis”(Agre et al., 2004). Several of the chapters in the latter Special …

Three aquaporins are expressed in the brain. AQP4, the predominant brain water channel,
is expressed in astrocyte endfeet facing brain capillaries, perisynaptic spaces, and nodes of …

Brain aquaporins facilitate the movement of water between the four water compartments:
blood, cerebrospinal fluid, interstitial fluid, and intracellular fluid. This work analyzes the …

Aquaporins (AQPs) are a family of water-selective channels that provide a major pathway for
osmotically driven water transport through cell membranes. Some members of the …

Background The presence of water channel proteins, aquaporins (AQPs), in the brain led to
intense research in understanding the underlying roles of each of them under normal …

The aquaporin channel family was first considered as a family of water channels, however it
is now clear that some of these channels are also permeable to small solutes such glycerol …