Adipose tissue represents a hot topic in regenerative medicine because of the tissue source
abundance, the relatively easy retrieval, and the inherent biological properties of …

In the field of orthopaedics, bone defects caused by severe trauma, infection, tumor
resection, and skeletal abnormalities are very common. However, due to the lengthy and …

Many bone regeneration therapies have been developed for clinical use and have variable
outcomes and serious limitations. The goal of bone regeneration is to repair a bone defect in …

Adipose stem cells (ASCs) are a crucial element in bone tissue engineering (BTE). They are
easy to harvest and isolate, and they are available in significative quantities, thus offering a …

Bone tissue engineering represents one of the most challenging emergent fields for
scientists and clinicians. Current failures of autografts and allografts in many pathological …

Bone regeneration is a complex process that is influenced by tissue interactions,
inflammatory responses, and progenitor cells. Diseases, lifestyle, or multiple trauma can …

The osteogenic and chondrogenic differentiation ability of adipose-derived mesenchymal
stromal cells (ASCs) and their potential therapeutic applications in bone and cartilage …

Introduction: Cell-based therapies exploit the heterogeneous and self-sufficient biological
environment of stem cells to restore, maintain and improve tissue functions. Adipose-derived …

Current treatment options for skeletal repair, including immobilization, rigid fixation,
alloplastic materials and bone grafts, have significant limitations. Bone tissue engineering …

Tissue engineering is now contributing to new developments in several clinical fields, and
mesenchymal stem cells derived from adipose tissue (hASCs) may provide a novel …