[HTML][HTML] Progressive bidirectional age-related changes in default mode network effective connectivity across six decades

K Li, AR Laird, LR Price, DR McKay… - Frontiers in aging …, 2016 - frontiersin.org
The default mode network (DMN) is a set of regions that is tonically engaged during the
resting state and exhibits task-related deactivation that is readily reproducible across a wide …

[HTML][HTML] Longitudinal functional connectivity patterns of the default mode network in healthy older adults

B Malagurski, PF Deschwanden, L Jäncke, S Mérillat - NeuroImage, 2022 - Elsevier
Cross-sectional studies have consistently identified age-associated alterations in default
mode network (DMN) functional connectivity (FC). Yet, research on longitudinal trajectories …

[HTML][HTML] Directed functional connectivity of the default-mode-network of young and older healthy subjects

G Goelman, R Dan, O Bezdicek, R Jech, D Ekstein - Scientific Reports, 2024 - nature.com
Alterations in the default mode network (DMN) are associated with aging. We assessed age-
dependent changes of DMN interactions and correlations with a battery of …

Longitudinal assessment of default-mode brain function in aging

J Persson, S Pudas, LG Nilsson, L Nyberg - Neurobiology of aging, 2014 - Elsevier
Age-related changes in the default-mode network (DMN) have been identified in prior cross-
sectional functional magnetic resonance imaging studies. Here, we investigated longitudinal …

The longitudinal trajectory of default mode network connectivity in healthy older adults varies as a function of age and is associated with changes in episodic memory …

AM Staffaroni, JA Brown, KB Casaletto… - Journal of …, 2018 - Soc Neuroscience
The default mode network (DMN) supports memory functioning and may be sensitive to
preclinical Alzheimer's pathology. Little is known, however, about the longitudinal trajectory …

[HTML][HTML] Decreased default mode network connectivity correlates with age-associated structural and cognitive changes

D Vidal-Piñeiro, C Valls-Pedret… - Frontiers in aging …, 2014 - frontiersin.org
Ageing entails cognitive and motor decline as well as brain changes such as loss of gray
(GM) and white matter (WM) integrity, neurovascular and functional connectivity alterations …

Age-related alterations in default mode network: impact on working memory performance

F Sambataro, VP Murty, JH Callicott, HY Tan, S Das… - Neurobiology of …, 2010 - Elsevier
The default mode network (DMN) is a set of functionally connected brain regions which
shows deactivation (task-induced deactivation, TID) during a cognitive task. Evidence shows …

Functional disintegration of the default mode network in prodromal Alzheimer's disease

KNH Dillen, HIL Jacobs, J Kukolja… - Journal of …, 2017 - content.iospress.com
Neurodegenerative brain changes can affect the functional connectivity strength between
nodes of the default-mode network (DMN), which may underlie changes in cognitive …

Older age is associated with a shift from ventral to dorsal PCC in pathways connecting the DMN with visual and limbic areas and a directionality shift in pathways …

G Goelman, R Dan, O Bezdicek, R Jech, D Ekstein - bioRxiv, 2022 - biorxiv.org
Alterations in the default mode network (DMN) are known to associated with aging and with
neurological and psychiatric diseases. We assessed age-dependent changes in interactions …

[HTML][HTML] The role of resting-state network functional connectivity in cognitive aging

HK Hausman, A O'Shea, JN Kraft… - Frontiers in Aging …, 2020 - frontiersin.org
Aging is associated with disruptions in the resting-state functional architecture of the brain.
Previous studies have primarily focused on age-related declines in the default mode …