[HTML][HTML] Emerging bacterial pathogens and changing concepts of bacterial pathogenesis in cystic fibrosis

MD Parkins, RA Floto - Journal of Cystic Fibrosis, 2015 - Elsevier
Chronic suppurative lower airway infection is a hallmark feature of cystic fibrosis (CF).
Decades of experience in clinical microbiology have enabled the development of improved …

Microbiology of cystic fibrosis airway disease

AC Blanchard, VJ Waters - Seminars in respiratory and critical …, 2019 - thieme-connect.com
Although survival of individuals with cystic fibrosis (CF) has been continuously improving for
the past 40 years, respiratory failure secondary to recurrent pulmonary infections remains …

Cystic fibrosis: a polymicrobial infectious disease

CD Sibley, H Rabin, MG Surette - Future microbiology, 2006 - Taylor & Francis
Cystic fibrosis (CF) is the most common lethal genetic disease in the Caucasian population,
and should be considered an infectious disease because of the basic pathophysiology …

[HTML][HTML] Cystic fibrosis microbiology: Advances in antimicrobial therapy

V Waters, A Smyth - Journal of cystic fibrosis, 2015 - Elsevier
Much of the improvement in the survival of individuals with cystic fibrosis (CF) is due to
advancements in antimicrobial treatments. New aerosolized antibiotic formulations have …

The changing microbial epidemiology in cystic fibrosis

JJ LiPuma - Clinical microbiology reviews, 2010 - Am Soc Microbiol
Infection of the airways remains the primary cause of morbidity and mortality in persons with
cystic fibrosis (CF). This review describes salient features of the epidemiologies of microbial …

The polymicrobial nature of airway infections in cystic fibrosis: Cangene Gold Medal Lecture

CD Sibley, MG Surette - Canadian journal of microbiology, 2011 - cdnsciencepub.com
Microbial communities characterize the airways of cystic fibrosis (CF) patients. Members of
these diverse and dynamic communities can be thought of as pathogens, benign …

The cystic fibrosis airway microbiome

HR Rabin, MG Surette - Current opinion in pulmonary medicine, 2012 - journals.lww.com
A comprehensive understanding of airway infections offers the potential for improved
disease management in CF patients. Accurate quantitative microbiology will be a …

[HTML][HTML] Microbial epidemiology of the cystic fibrosis airways: past, present, and future

CS Thornton, MD Parkins - Seminars in Respiratory and …, 2023 - thieme-connect.com
Progressive obstructive lung disease secondary to chronic airway infection, coupled with
impaired host immunity, is the leading cause of morbidity and mortality in cystic fibrosis (CF) …

[HTML][HTML] Pathogenicity of microbes associated with cystic fibrosis

ML Hutchison, JRW Govan - Microbes and Infection, 1999 - Elsevier
Cystic fibrosis patients are exceptionally prone to colonisation by a narrow spectrum of
pathogenic bacteria. Since pulmonary infection presently, and for the foreseeable future …

Phylogenetic and metabolic diversity of bacteria associated with cystic fibrosis

AM Guss, G Roeselers, ILG Newton, CR Young… - The ISME …, 2011 - academic.oup.com
In patients afflicted with cystic fibrosis (CF), morbidity and mortality are primarily associated
with the adverse consequences of chronic microbial bronchial infections, which are thought …