Abstract Background Inflammatory bowel diseases (IBDs) such as Crohn's disease and
ulcerative colitis are characterized by recurrent inflammation in the gastrointestinal tract …

Background & Aims: Interleukin (IL)-21, a T-cell-derived cytokine, is overproduced in
inflammatory bowel diseases (IBD), but its role in the pathogenesis of gut inflammation …

Background T helper (TH) 17 cells are believed to play a pivotal role in development of
inflammatory bowel disease, and their contribution to intestinal inflammation has been …

Background & Aims: Interleukin (IL)-16 is a T lymphocyte-derived cytokine that uses CD4 as
its receptor and hence selectively recruits CD4-bearing cells. Infiltrating CD4+ T cells are a …

Abstract Interleukin (IL)-17C is a novel member of the IL-17 cytokine family. Its function in
human inflammatory bowel disease (IBD) remains elusive as its role in colonic inflammation …

This study analyzed IL-23p19 expression in inflamed mucosa of IBD and the role in the
induction of IEL and NK cell activation as well as Th17 cell differentiation. Expression of IL …

Although very high levels of interleukin (IL)-1β are present in the intestines of patients
suffering from inflammatory bowel diseases (IBD), little is known about the contribution of IL …

T helper type (Th17) cytokines such as interleukin (IL)-17A and IL-22 are important in
maintaining mucosal barrier function and may be important in the pathogenesis of …

Inflammatory bowel diseases (IBDs) are chronic disorders of modern society, requiring
management strategies aimed at prolonging an active life and establishing the exact …

Results of experimental and genetic studies have highlighted the role of the IL-23/IL-17 axis
in the pathogenesis of inflammatory bowel disease (IBD). IL-23–driven inflammation has …