Immunoinformatics-guided designing of epitope-based subunit vaccine from Pilus assembly protein of Acinetobacter baumannii bacteria

SR Mahapatra, J Dey, A Jaiswal, R Roy, N Misra… - Journal of …, 2022 - Elsevier
Acinetobacter baumannii, a prominent pathogen responsible for chronic infections in the
blood, urinary tract, and lungs, has a high mortality due to its virulence and limited …

[HTML][HTML] Immunoprotective Efficacy of Acinetobacter baumannii Outer Membrane Protein, FilF, Predicted In silico as a Potential Vaccine Candidate

R Singh, N Garg, G Shukla, N Capalash… - Frontiers in …, 2016 - frontiersin.org
Acinetobacter baumannii is emerging as a serious nosocomial pathogen with multidrug
resistance that has made it difficult to cure and development of efficacious treatment against …

[HTML][HTML] Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based …

J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …

[HTML][HTML] Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii

M Ud-Din, A Albutti, A Ullah, S Ismail, S Ahmad… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …

[HTML][HTML] In-Silico Vaccine Design Based on a Novel Vaccine Candidate Against Infections Caused by Acinetobacter baumannii

K Khalid, S Irum, SR Ullah, S Andleeb - International journal of peptide …, 2022 - Springer
Acinetobacter baumannii is notorious for causing serious infections of the skin, lungs, soft
tissues, bloodstream, and urinary tract. Despite the overwhelming information available so …

Design and evaluation of a multi-epitope assembly peptide vaccine against Acinetobacter baumannii infection in mice

S Ren, L Guan, Y Dong, C Wang, L Feng, Y Xie - Swiss medical weekly, 2019 - smw.ch
AIM To design a multi-epitope assembly peptide (MEP) of Acinetobacter baumannii and
evaluate its immunogenicity and protective immunity in Balb/c mice. METHODS The T-and B …

[HTML][HTML] Designing Multi-Antigen Vaccines Against Acinetobacter baumannii Using Systemic Approaches

MJ McConnell, AJ Martín-Galiano - Frontiers in Immunology, 2021 - frontiersin.org
Vaccines and monoclonal antibodies are promising approaches for preventing and treating
infections caused by multidrug resistant Acinetobacter baumannii. However, only partial …

Immunoinformatics and molecular docking studies reveal a novel Multi-Epitope peptide vaccine against pneumonia infection

SR Mahapatra, J Dey, T Kaur, R Sarangi, AA Bajoria… - Vaccine, 2021 - Elsevier
Pneumonia is a major endemic disease around the world, and an effective vaccine is the
need of the hour to fight against the disease. When there are no appropriate antiviral and …

[HTML][HTML] Pangenome and immuno-proteomics analysis of Acinetobacter baumannii strains revealed the core peptide vaccine targets

A Hassan, A Naz, A Obaid, RZ Paracha, K Naz… - BMC genomics, 2016 - Springer
Background Acinetobacter baumannii has emerged as a significant nosocomial pathogen
during the last few years, exhibiting resistance to almost all major classes of antibiotics …

[HTML][HTML] Subtractive proteomics to identify novel drug targets and reverse vaccinology for the development of chimeric vaccine against Acinetobacter baumannii

V Solanki, V Tiwari - Scientific reports, 2018 - nature.com
The emergence of drug-resistant Acinetobacter baumannii is the global health problem
associated with high mortality and morbidity. Therefore it is high time to find a suitable …