In the last 2 decades, Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) has
gained significant prominence as a powerful imaging technique in the field of life sciences …

Time-of-flight secondary ion mass spectrometry (ToF–SIMS) imaging is an analytical
technique rapidly expanding in use in biological studies. This technique is based on high …

Secondary ion mass spectrometry (SIMS) has been increasingly recognized as a powerful
technique for visualizing molecular architectures in the fields of neurobiology and cell …

This brief article provides an overview of the current state of the art in biological imaging
mass spectrometry using cluster time-of-flight secondary ion mass spectrometry (TOF …

Fundamental advances in secondary ion mass spectrometry (SIMS) now allow for the
examination and characterization of lipids directly from biological materials. The successful …

Single cell imaging mass spectrometry opens up a complete new perspective for strategies
in toxicological risk assessment and drug discovery. In particular, time-of-flight secondary …

Secondary ion mass spectrometry, including nanoscale secondary ion mass spectrometry
(NanoSIMS) and time-of-flight secondary ion mass spectrometry (ToF–SIMS), has emerged …

The ability to image cells and tissues with chemical and molecular specificity could greatly
expand our understanding of biological processes. The subcellular resolution mass spectral …

Imaging by secondary ion mass spectrometry coupled to time-of-flight mass analysis (TOF-
SIMS) is a method of which the applications have greatly increased since 10 years. Taking …

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has unique capabilities in the
area of high-resolution mass spectrometric imaging of biological samples. The technique …