Misfolded proteins in the central nervous system can induce oxidative damage, which can
contribute to neurodegenerative diseases in the mitochondria. Neurodegenerative patients …

Mitochondria are involved in ATP supply to cells through oxidative phosphorylation
(OXPHOS), synthesis of key molecules and response to oxidative stress, as well as in …

Mitochondria play a critical role in several metabolic processes and apoptotic pathways,
regulating life cycle from the cradle to the grave. Despite the evidence of morphological …

Mitochondria are implicated in several metabolic pathways including cell respiratory
processes, apoptosis, and free radical production. Mitochondrial abnormalities have been …

Mitochondria play a critical role in neuron viability or death as it regulates energy
metabolism and cell death pathways. They are essential for cellular energy metabolism …

Many lines of evidence suggest that mitochondria have a central role in ageing-related
neurodegenerative diseases. However, despite the evidence of morphological, biochemical …

Mitochondrial dysfunction plays a very vital role in the pathogenesis of Alzheimer's disease
(AD). Several shreds of evidence have indicated that the mitochondrial function is severely …

Fundamental organelles that occur in every cell type with the exception of mammal
erythrocytes, the mitochondria are required for multiple pivotal processes that include the …

Mitochondria play a central role in a plethora of processes related to the maintenance of
cellular homeostasis and genomic integrity. They contribute to preserving the optimal …

Abstract Alzheimer's disease (AD), the most common form of dementia, is thought to be
associated with multiple factors, where the greatest risk factor is aging. Several traditional …