Harnessing the angiogenic potential of stem cell‐derived exosomes for vascular regeneration

F Alcayaga-Miranda, M Varas-Godoy… - Stem cells …, 2016 - Wiley Online Library
Mesenchymal stem cells (MSCs) are known to display important regenerative properties
through the secretion of proangiogenic factors. Recent evidence pointed at the key role …

Mesenchymal stem cell-derived extracellular vesicles promote angiogenesis: potencial clinical application

C Merino-González, FA Zuñiga, C Escudero… - Frontiers in …, 2016 - frontiersin.org
Mesenchymal stem cells (MSCs) are adult multipotent stem cells that are able to differentiate
into multiple specialized cell types including osteocytes, adipocytes, and chondrocytes …

[HTML][HTML] Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis

M Gong, B Yu, J Wang, Y Wang, M Liu, C Paul… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have been found to benefit patients with a variety of
ischemic diseases via promoting angiogenesis. It is also well established that exosomes …

Application of stem cell-derived exosomes in ischemic diseases: opportunity and limitations

M Babaei, J Rezaie - Journal of translational medicine, 2021 - Springer
Ischemic diseases characterized by an insufficient blood flow that leads to a decrease in
oxygen and nutrient uptake by cells have emerged as an important contributor to both …

Exosomes from mesenchymal stem cells expressing miR‐125b inhibit neointimal hyperplasia via myosin IE

D Wang, B Gao, J Yue, F Liu, Y Liu… - Journal of Cellular and …, 2019 - Wiley Online Library
Intercellular communication between mesenchymal stem cells (MSC s) and their target cells
in the perivascular environment is modulated by exosomes derived from MSC s. However …

Exosomes derived from mesenchymal stem cells suppress angiogenesis by down-regulating VEGF expression in breast cancer cells

JK Lee, SR Park, BK Jung, YK Jeon, YS Lee, MK Kim… - PloS one, 2013 - journals.plos.org
Exosomes are small membrane vesicles released by a variety of cell types. Exosomes
contain genetic materials, such as mRNAs and microRNAs (miRNAs), implying that they …

Comprehensive proteomic analysis of mesenchymal stem cell exosomes reveals modulation of angiogenesis via nuclear factor-kappaB signaling

JD Anderson, HJ Johansson, CS Graham… - Stem …, 2016 - academic.oup.com
Mesenchymal stem cells (MSC) are known to facilitate healing of ischemic tissue related
diseases through proangiogenic secretory proteins. Recent studies further show that MSC …

Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

S Nikfarjam, J Rezaie, NM Zolbanin, R Jafari - Journal of translational …, 2020 - Springer
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …

The development of stem cell-derived exosomes as a cell-free regenerative medicine

I Vishnubhatla, R Corteling… - Journal of …, 2014 - journals.sagepub.com
A successful strategy in regenerative medicine over the last decade has been the translation
of stem cell therapy to repair diseased or damaged tissue in a wide range of indications …

Role of MSC‐derived small extracellular vesicles in tissue repair and regeneration

BA Aguiar Koga, LA Fernandes, P Fratini… - Frontiers in Cell and …, 2023 - frontiersin.org
Mesenchymal stem cells (MSCs) are crucial for tissue homeostasis and repair, secreting
vesicles to the extracellular environment. Isolated exosomes were shown to affect …