Joint injuries are common, especially among young adults aged 18 to 44 years. They are
accompanied by a cascade of events that increase the risk of posttraumatic osteoarthritis …

The goals of all orthopaedic surgeons treating articular cartilage injuries have been
anatomic reduction and stable fixation of the articular cartilage surface with restoration of …

Traumatic injuries of the knee joint result in a wide variety of pathomechanisms, which
contribute to the development of so-called posttraumatic osteoarthritis (PTOA). These …

Osteoarthritis, as distinguished from arthritis secondary to inflammatory or neurologic
disorders, is the most common form of joint disease and is one of the leading causes of …

Post-traumatic osteoarthritis (PTOA) develops secondary to a joint injury and accounts for
12% of all osteoarthritis. These injuries, often of the lower extremity joints, occur due to …

Articular cartilage degeneration, for example, resulting from joint injury and trauma, has
remained a major clinical challenge as cartilage does not have self-healing capability, and …

Osteoarthritis affects millions of people worldwide, is associated with joint stiffness and pain,
and often causes significant disability and loss of productivity. Osteoarthritis is believed to …

Objective A number of in vitro models of post-traumatic osteoarthritis (PTOA) have been
developed to study the effect of mechanical overload on the processes that regulate …

Osteoarthritis (OA) is characterized by joint pain and stiffness with radiographic evidence of
joint space narrowing, osteophytes, and subchondral bone sclerosis. Posttraumatic OA …

Articular cartilage is a highly specialized tissue whose remarkable properties of
deformability, resistance to mechanical loading, and low-friction gliding are essential to joint …