Multicomponent reactions have emerged as an important approach for the synthesis of
diverse and complicated chemical compounds. They have various advantages over two …

Herein, we report the synthesis and characterization of 1–16 new naphthalimide derivatives.
These compounds 1–16 were tested for their anticancer activity against cancerous cells …

To explore the anticancer compounds from tormentic acid derivatives, a quantitative
structure–activity relationship (QSAR) model was developed by the multiple linear …

Cancer is a leading threatful disease worldwide. Research focused on natural compounds
for anticancer drugs has facilitated the identification of numerous medications presently …

Background: Molecules bearing an active methylene bridge are one of the most fruitful and
remarkable precursors that have been incorporated into the synthetic strategy of an …

Abstract The 5-isopropyl-2-methylphenol (5IP2MP) molecule, a monoterpenoid phenol
mostly existing in the essential oil of Origanum vulgare L., was used as a potent breast …

A series of new acylhydrazone derivatives were synthesized from the condensation of
different substituted salicylaldehydes with 4‐nitrobenzohydrazide at a molar ratio of 1: 1 in a …

Colon cancer remains a significant health concern, necessitating the synthesis of novel
therapeutic agents. Benzimidazole derivatives have shown promising anticancer potential …

One of the current approaches used in drug discovery and development is the synthesis of
novel small compounds from existing structural motifs via molecular hybridization. In the …

A series of piperazine bearing thiourea compounds with different substitutions (L1-L13) was
synthesized for the treatment of colorectal carcinoma. The spectroscopic characterizations …