DNA damage, serum metabolomic alteration and carcinogenic risk associated with low-level air pollution

J Xu, Y Liu, Q Zhang, Z Su, T Yan, S Zhou, T Wang… - Environmental …, 2022 - Elsevier
Outdoor air pollution has been classified as carcinogenic to humans (Group 1) for lung
cancer, but the underlying mechanism and key toxic components remain incompletely …

[HTML][HTML] Genetic damage and potential mechanism exploration under different air pollution patterns by multi-omics

J Xu, Q Zhang, Z Su, Y Liu, T Yan, Y Zhang… - Environment …, 2022 - Elsevier
Ambient air pollution was classified as carcinogenic to humans (Group 1) for lung cancer.
DNA damage was an important first step in the process of carcinogenesis, and could also be …

Effects of environmental air pollution on endogenous oxidative DNA damage in humans

R Singh, B Kaur, I Kalina, TA Popov… - Mutation Research …, 2007 - Elsevier
Epidemiological studies conducted in metropolitan areas have demonstrated that exposure
to environmental air pollution is associated with increases in mortality. Carcinogenic …

Oxidative damage to DNA and lipids as biomarkers of exposure to air pollution

P Møller, S Loft - Environmental health perspectives, 2010 - ehp.niehs.nih.gov
Background Air pollution is thought to exert health effects through oxidative stress, which
causes damage to DNA and lipids. Objective We determined whether levels of oxidatively …

[HTML][HTML] Carcinogenicity of ambient air pollution: use of biomarkers, lessons learnt and future directions

CA Demetriou, P Vineis - Journal of thoracic disease, 2015 - ncbi.nlm.nih.gov
The association between ambient air pollution (AAP) exposure and lung cancer risk has
been investigated in prospective studies and the results are generally consistent, indicating …

Air pollution and cancer: biomarker studies in human populations

P Vineis, K Husgafvel-Pursiainen - Carcinogenesis, 2005 - academic.oup.com
Large cohort studies in the US and in Europe suggest that air pollution may increase lung
cancer risk. Biomarkers can be useful to understand the mechanisms and to characterize …

[HTML][HTML] Environmental DNA and RNA as records of human exposome, including biotic/abiotic exposures and its implications in the assessment of the role of …

IS Thakur, D Roy - International Journal of Molecular Sciences, 2020 - mdpi.com
Most of environment-related diseases often result from multiple exposures of abiotic and/or
biotic stressors across various life stages. The application of environmental DNA/RNA …

A toxicogenomic comparison of primary and photochemically altered air pollutant mixtures

JE Rager, K Lichtveld, S Ebersviller… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Air pollution contributes significantly to global increases in mortality,
particularly within urban environments. Limited knowledge exists on the mechanisms …

[HTML][HTML] Air pollution and epigenetics: recent findings

CV Breton, AN Marutani - Current environmental health reports, 2014 - Springer
The health effects of ambient air pollution are well-described, but less is known about the
biological mechanisms mediating these health effects. In recent years, the hypothesis that …

Blood-borne biomarkers and bioindicators for linking exposure to health effects in environmental health science

MAG Wallace, TM Kormos, JD Pleil - Journal of Toxicology and …, 2016 - Taylor & Francis
Environmental health science aims to link environmental pollution sources to adverse health
outcomes to develop effective exposure intervention strategies that reduce long-term …