Geographical variations in sex ratio trends over time in multiple sclerosis

M Trojano, G Lucchese, G Graziano, BV Taylor… - PloS one, 2012 - journals.plos.org
Background A female/male (F/M) ratio increase over time in multiple sclerosis (MS) patients
was demonstrated in many countries around the world. So far, a direct comparison of sex …

Sex ratio of multiple sclerosis in the National Swedish MS Register (SMSreg)

I Boström, L Stawiarz… - Multiple sclerosis …, 2013 - journals.sagepub.com
Background: Sex ratio in multiple sclerosis has been reported from several geographical
areas. The disease is more common in women. In Europe the female-to-male ratio varies …

New data identify an increasing sex ratio of multiple sclerosis in Sweden

H Westerlind, I Boström, L Stawiarz… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Background: An increasing women-to-men ratio in later birth cohorts of patients with multiple
sclerosis (MS) has been observed in several populations and has been hypothesised to be …

Sex ratio of multiple sclerosis and clinical phenotype

SV Ramagopalan, JK Byrnes, SM Orton… - European journal of …, 2010 - Wiley Online Library
Background and purpose: In a longitudinal population‐based dataset of patients with
multiple sclerosis (MS), we have previously observed a substantial increase in the female to …

Effect of immigration on multiple sclerosis sex ratio in Canada: the Canadian Collaborative Study

SM Orton, SV Ramagopalan, D Brocklebank… - Journal of Neurology …, 2010 - jnnp.bmj.com
Background: The ratio of female to male (F: M) multiple sclerosis (MS) cases varies
geographically, generally being greater in areas of high prevalence. In many regions …

Sex ratio of multiple sclerosis in Canada: a longitudinal study

SM Orton, BM Herrera, IM Yee, W Valdar… - The Lancet …, 2006 - thelancet.com
Background Incidence of multiple sclerosis is thought to be increasing, but this notion has
been difficult to substantiate. In a longitudinal population-based dataset of patients with …

Change in sex ratio, disease course and age at diagnosis in Oslo MS patients through seven decades

EG Celius, C Smestad - Acta Neurologica Scandinavica, 2009 - Wiley Online Library
Objectives–To study changes in sex ratio, disease course, time from onset to diagnosis and
age at diagnosis by year of birth in a well‐defined population of multiple sclerosis (MS) …

Increasing female preponderance of multiple sclerosis in Isfahan, Iran: a population-based study

AH Maghzi, H Ghazavi, M Ahsan… - Multiple Sclerosis …, 2010 - journals.sagepub.com
There is an overall increase in the worldwide prevalence and incidence of multiple sclerosis
(MS). Studies from several countries also demonstrated an increase of female/male ratio …

The importance of studying sex differences in disease: The example of multiple sclerosis

LC Golden, R Voskuhl - Journal of neuroscience research, 2017 - Wiley Online Library
To date, scientific research has often focused on one sex, with assumptions that study of the
other sex would yield similar results. However, many diseases affect males and females …

Male sex is independently associated with faster disability accumulation in relapse-onset MS but not in primary progressive MS

KA Ribbons, P McElduff, C Boz, M Trojano… - PloS one, 2015 - journals.plos.org
Background Multiple Sclerosis is more common in women than men and females have more
relapses than men. In a large international cohort we have evaluated the effect of gender on …