Background The natriuretic peptide family consists of four molecules that share significant
amino acid sequence homologic characteristics and a looped motif. Atrial natriuretic peptide …

Cardiac natriuretic peptides are a family of structurally related peptides that are important in
sodium and volume homeostasis. They consist of atrial natriuretic peptide, brain natriuretic …

The natriuretic peptide system includes three known peptides: atrial natriuretic peptide
(ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). They contribute …

1. The major cardiovascular and renal actions of α-atrial natriuretic peptide (ANP) and brain
natriuretic peptide (BNP) and the fact that the heart is strategically located to sense changes …

Investigations into the mixed muscle–secretory phenotype of cardiomyocytes from the atrial
appendages of the heart led to the discovery that these cells produce, in a regulated …

The discovery of the natriuretic peptide family was a breakthrough in modern cardiovascular
physiology as it provided a direct link between the heart and the kidneys in the regulation of …

Background The natriuretic peptides are counterregulatory hormones involved in volume
homeostasis and cardiovascular remodeling. The prognostic significance of plasma …

Since the discovery of atrial natriuretic factor by de Bold et al., there has been tremendous
progress in our understanding of the physiologic, diagnostic and therapeutic roles of the …

Cardiac natriuretic peptides contribute importantly to the maintenance of sodium and volume
homeostasis in health and disease. The hemodynamic, renal, and endocrinologic effects of …

Natriuretic peptides (BNP and NT‐proBNP) have been shown to be useful tools for risk
stratification of patients with acute myocardial ischemia encompassing the whole spectrum …