Hydroxytyrosol plays antiatherosclerotic effects through regulating lipid metabolism via inhibiting the p38 signal pathway
X Zhang, Y Qin, X Wan, H Liu, C Iv… - BioMed Research …, 2020 - Wiley Online Library
Purpose. Hydroxytyrosol (HT) processes multiaspect pharmacological properties such as
antithrombosis and antidiabetes. The aim of this study was to explore the antistherosclerotic …
antithrombosis and antidiabetes. The aim of this study was to explore the antistherosclerotic …
Wide biological role of hydroxytyrosol: possible therapeutic and preventive properties in cardiovascular diseases
C D'Angelo, S Franceschelli, JL Quiles, L Speranza - Cells, 2020 - mdpi.com
The growing incidence of cardiovascular disease (CVD) has promoted investigations of
natural molecules that could prevent and treat CVD. Among these, hydroxytyrosol, a …
natural molecules that could prevent and treat CVD. Among these, hydroxytyrosol, a …
Molecular action of hydroxytyrosol in attenuation of intimal hyperplasia: a scoping review
U Vijakumaran, MD Yazid, RB Hj Idrus… - Frontiers in …, 2021 - frontiersin.org
Objective: Hydroxytyrosol (HT), a polyphenol of olive plant is well known for its antioxidant,
anti-inflammatory and anti-atherogenic properties. The aim of this systematic search is to …
anti-inflammatory and anti-atherogenic properties. The aim of this systematic search is to …
Hydroxytyrosol Reduces Foam Cell Formation and Endothelial Inflammation Regulating the PPARγ/LXRα/ABCA1 Pathway
S Franceschelli, F De Cecco, M Pesce, P Ripari… - International journal of …, 2023 - mdpi.com
Cholesterol accumulation in macrophages leads to the formation of foam cells and
increases the risk of developing atherosclerosis. We have verified whether hydroxytyrosol …
increases the risk of developing atherosclerosis. We have verified whether hydroxytyrosol …
Hydroxytyrosol and its main plasma circulating metabolites attenuate the initial steps of atherosclerosis through inhibition of the MAPK pathway
The main aim of this work is to gain insight into the potential mechanisms of hydroxytyrosol
(HT) and its main plasmatic metabolites (HTmet) that improve the endothelial function …
(HT) and its main plasmatic metabolites (HTmet) that improve the endothelial function …
3-Hydroxytyrosol promotes angiogenesis in vitro by stimulating endothelial cell migration
M Abate, S Pisanti, M Caputo, M Citro… - International Journal of …, 2020 - mdpi.com
Cardiovascular diseases, followed by strokes, represent the leading cause of mortality
worldwide. Despite its success in preventing cardiovascular diseases, the therapeutic …
worldwide. Despite its success in preventing cardiovascular diseases, the therapeutic …
Effects of hydroxytyrosol in endothelial functioning: a comprehensive review
U Vijakumaran, J Shanmugam, JW Heng, SS Azman… - Molecules, 2023 - mdpi.com
Pharmacologists have been emphasizing and applying plant and herbal-based treatments
in vascular diseases for decades now. Olives, for example, are a traditional symbol of the …
in vascular diseases for decades now. Olives, for example, are a traditional symbol of the …
Hydroxytyrosol reduces intracellular reactive oxygen species levels in vascular endothelial cells by upregulating catalase expression through the AMPK–FOXO3a …
H Zrelli, M Matsuoka, S Kitazaki, M Zarrouk… - European Journal of …, 2011 - Elsevier
Reactive oxygen species are critically involved in the endothelial dysfunction that
contributes to atherosclerosis development. Hydroxytyrosol (HT), a main phenolic …
contributes to atherosclerosis development. Hydroxytyrosol (HT), a main phenolic …
Hydroxytyrosol modulates adipocyte gene and miRNA expression under inflammatory condition
Chronic inflammation of the adipose tissue (AT) is a major contributor to obesity-associated
cardiometabolic complications. The olive oil polyphenol hydroxytyrosol (HT) contributes to …
cardiometabolic complications. The olive oil polyphenol hydroxytyrosol (HT) contributes to …
Hydroxytyrosol: Its role in the prevention of cardiovascular diseases
C Noguera-Navarro, S Montoro-García… - Heliyon, 2023 - cell.com
In recent years, non-pharmacology treatments and their effectiveness have gained
popularity due to their beneficial properties in the prevention of cardiovascular diseases …
popularity due to their beneficial properties in the prevention of cardiovascular diseases …