Amphipols are amphipathic polymers that stabilize membrane proteins isolated from their
native membrane. They have been functionalized with various chemical groups in the past …

Because of the importance of their physiological functions, cell membranes represent critical
targets in biological research. Membrane proteins, which make up≈ 1/3 of the proteome …

Amphipols (APols) are short amphipathic polymers that stabilize membrane proteins (MPs)
in aqueous solutions. In the present study, A8–35, a polyacrylate-based APol, was grafted …

Amphipols (APols) are short amphipathic polymers developed as an alternative to
detergents for handling membrane proteins (MPs) in aqueous solution. MPs are, as a rule …

This book is the first to be entirely devoted to the challenging art of handling membrane
proteins out of their natural environment, a key process in biological and pharmaceutical …

Membrane proteins classically are handled in aqueous solutions as complexes with
detergents. The dissociating character of detergents, combined with the need to maintain an …

Amphipathic polymers called amphipols provide a valuable alternative to detergents for
keeping integral membrane proteins soluble in aqueous buffers. Here, we characterize …

Amphipols (APols) are short amphipathic polymers designed to adsorb onto the
transmembrane surface of membrane proteins, keeping them water-soluble in the absence …

Amphiphilic macromolecules, known as amphipols, have emerged as promising candidates
to replace conventional detergents for handling integral membrane proteins in water due to …

Amphipols (APols) are a family of amphipathic polymers designed to keep transmembrane
proteins (TMPs) soluble in aqueous solutions in the absence of detergent. APols have …