Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype …

H Shiku, P Kisielow, MA Bean, T Takahashi… - The Journal of …, 1975 - rupress.org
The cell-mediated cytotoxicity (CMC) of nonadherent cells from the peritoneal cavity (NAPC)
of alloimmunized mice can be measured by the [3H] proline microassay. The exhibition of …

Surface antigens on mouse natural killer cells: use of monoclonal antibodies to inhibit or to enrich cytotoxic activity.

WE Seaman, N Talal, LA Herzenberg… - … (Baltimore, Md.: 1950 …, 1981 - journals.aai.org
In studies using monoclonal antibodies to cell-surface antigens we have identified 2 new
antigens (H11 and 7.2) expressed on mouse NK cells. These are shared with T cells but not …

[引用][C] Evidence for T cell nature and heterogeneity within natural killer (NK) and antibody-dependent cellular cytotoxicity (ADCC) effectors: a comparison with cytolytic …

LD Fast, JA Hansen, W Newman - Journal of immunology …, 1981 - journals.aai.org
MATERIALS AND METHODS Peripheral blood rnononucfear cell purification. Peripheral
blood lymphocytes (PBL) cells were obtained from heparinized blood of normal volunteers …

Protein-antigen specific Ia-restricted cytolytic T cells: analysis of frequency, target cell susceptibility, and mechanism of cytolysis.

JP Tite, MB Powell, NH Ruddle - Journal of immunology (Baltimore …, 1985 - journals.aai.org
We previously showed that cloned, antigen-specific, Ia-restricted L3T4a+ T cell lines can be
cytolytic for antigen-pulsed B cell lymphoma targets. Such cells can also, under different …

CELLS MEDIATING SPECIFIC IN VITRO CYTOTOXICITY: II. PROBABLE AUTONOMY OF THYMUS-PROCESSED LYMPHOCYTES (TCELLS) FOR THE KILLING OF ALLOGENEIC T …

P Golstein, H Wigzell, H Blomgren… - The Journal of …, 1972 - rupress.org
In order to investigate whether only T cells are involved in a cell-mediated cytotoxic system
in vitro, we tested the cytotoxicity of immune killing cell populations as deprived as possible …

Evidence for direct linkage between antigen recognition and lytic expression in effector T cells.

RC Kuppers, CS Henney - The Journal of experimental medicine, 1976 - rupress.org
The relationship between antigen recognition and lytic expression by effector T cells was
examined by coculturing two cytolytically active lymphoid cell populations. When antigen …

[PDF][PDF] The role of T cell differentiation markers in antigen-specific and lectin-dependent cellular cytotoxicity mediated by T8+ and T4+ human cytotoxic T cell clones …

H Spits, J Borst, C Terhorst… - Journal of immunology …, 1982 - researchgate.net
MATERIALS AND METHODS D-MEM supplemented with 2 x 1 0-5 M ethanolamine (Merck,
Darmstadt. Media andreagents. All cell cultures were carried out in Iscove's modified West …

Presence of T cell-associated surface antigens on murine NK cells

SB Pollack, MR Tam, RC Nowinski… - The Journal of …, 1979 - journals.aai.org
The expression of T cell-associated surface antigens on natural killer (NK) spleen cells of
C57BL/6 mice was evaluated by cytotoxic depletion experiments with alloantisera prepared …

Inhibition of murine T cell‐mediated cytolysis and T cell proliferation by a rat monoclonal antibody immunoprecipitating two lymphoid cell surface polypeptides of …

M Pierres, C Goridis, P Golstein - European Journal of …, 1982 - Wiley Online Library
The monoclonal antibody methodology was used to identify membrane structures involved
in T cell functions. To optimize chances to produce and detect relevant antibodies, a …

Studies on the induction and expression of T cell-mediated immunity. X. Inhibition by Lyt 2, 3 antisera of cytotoxic T lymphocyte-mediated antigen-specific and …

J Fan, A Ahmed, B Bonavida - Journal of immunology (Baltimore …, 1980 - journals.aai.org
The role of cell surface alloantigens of murine cytotoxic T lymphocytes (CTL) and the
molecular interactions requisite for CTL-mediated target cell lysis were investigated with …