The role of TRPV4 (transient receptor potential vanilloid 4) in regulating vascular contraction
in hypertensive mice is poorly established. We tested the hypothesis that TRPV4 regulates …

Recent studies have focused on the contribution of vascular endothelial transient receptor
potential vanilloid 4 (TRPV4) channels to hypertension. However, in hypertension, TRPV4 …

We investigated the effect of arginine vasopressin (AVP) on inorganic phosphate (Pi)
transport in A-10 rat aortic vascular smooth muscle cells (VSMCs). AVP time-and dose …

AIM: The ability of the thyroid hormone to increase cardiac output and to lower systemic
vascular resistance may provide a novel treatment for cardiovascular diseases. Therefore …

Abstract Inositol 1, 4, 5-trisphosphate receptor–mediated (IP 3 R-mediated) calcium (Ca 2+)
release has been proposed to play an important role in regulating vascular smooth muscle …

Aims Transient receptor potential vanilloid 2 (TRPV2) channels are expressed in both
smooth muscle and endothelial cells and participate in vascular mechanotransduction and …

Thyroid dysfunction is associated with elevated cardiovascular risk factors and
atherosclerosis. It could be suggested that, hyperthyroidism is related to a higher prevalence …

Aims Vascular endothelial cells synthesize and release vasodilators such as nitric oxide
(NO) and epoxyeicosatrienoic acids (EETs). NO is known to inhibit EET-induced smooth …

Phosphatidylinositol 3-kinase (PI3K) has been implicated in low extracellular Mg2+
concentration ([Mg2+] e)–induced aortic contraction, and Mg2+ deficiency has been …

Propylthiouracil (PTU), independent of its antithyroid effect, is recently found to have an
antiatherosclerotic effect. The aim of this study is to determine the impact of PTU on …