[HTML][HTML] Taurine suppresses platelet-derived growth factor (PDGF) BB-induced PDGF-β receptor phosphorylation by protein tyrosine phosphatase-mediated …

H Yoshimura, Y Nariai, M Terashima, T Mitani… - … et Biophysica Acta (BBA …, 2005 - Elsevier
In atherosclerosis, abnormal vascular smooth muscle cell (VSMC) proliferation plays an
important role to form fibroproliferative lesions and platelet-derived growth factor (PDGF)-BB …

The transient receptor potential vanilloid‐3 regulates hypoxia‐mediated pulmonary artery smooth muscle cells proliferation via PI 3K/AKT signaling pathway

Q Zhang, Y Cao, Q Luo, P Wang, P Shi… - Cell …, 2018 - Wiley Online Library
Objectves Transient receptor potential vanilloid 3 (TRPV 3) is a member of the TRP
channels family of Ca2+‐permeant cation channels. In this study, we aim to investigate the …

Thyroid hormones affect nitrergic innervation function in rat mesenteric artery: role of the PI3K/AKT pathway

P Llévenes, G Balfagón, J Blanco-Rivero - Vascular pharmacology, 2018 - Elsevier
We aimed to determine the influence of nitrergic innervation function on the decreased
mesenteric arterial tone induced by high levels of triiodothyronine (T3), as a model of acute …

Thyroid hormone inhibits vascular remodeling through suppression of cAMP response element binding protein activity

K Fukuyama, T Ichiki, I Imayama… - … and Vascular Biology, 2006 - Am Heart Assoc
Objective—Although accumulating evidences suggest that impaired thyroid function is a risk
for ischemic heart disease, the molecular mechanism of anti-atherosclerotic effects of thyroid …

Thyroid hormone induces artery smooth muscle cell proliferation: discovery of a new TRα1‐Nox1 pathway

X Wang, Z Sun - Journal of cellular and molecular medicine, 2010 - Wiley Online Library
Thyroid hormone (T3) can stimulate protein synthesis and cell growth. NOX1 is a mitogenic
oxidase. The aim of this study was to test a novel hypothesis that T3 induces artery smooth …

Thyroid hormone promotes remodeling of coronary resistance vessels

OV Savinova, Y Liu, GA Aasen, K Mao, NY Weltman… - PloS one, 2011 - journals.plos.org
Low thyroid hormone (TH) function has been linked to impaired coronary blood flow,
reduced density of small arterioles, and heart failure. Nonetheless, little is known about the …

[PDF][PDF] The stimulative effect of T3 and T4 on human myocardial endothelial cell proliferation, migration and angiogenesis

S Balzan, R Del Carratore, C Nardulli… - J. Clin. Exp …, 2013 - researchgate.net
Angiogenesis, the process involving the growth of new blood vessels from pre-existing
vessels, may be a target for combating diseases characterized by either poor vascularisation …

Vascular function of the mesenteric artery isolated from thyroid hormone receptor-E knockout mice

KL Liu, M Lo, L Canaple, K Gauthier… - Journal of vascular …, 2015 - karger.com
Objective: This study evaluated the consequences of thyroid hormone receptor-E (TRE)
disruption on vascular reactivity. Methods: The activity of superior mesenteric arteries …

Uric acid stimulates proliferative pathways in vascular smooth muscle cells through the activation of p38 MAPK, p44/42 MAPK and PDGFRβ

M Kırça, N Oğuz, A Çetin, F Uzuner… - Journal of Receptors …, 2017 - Taylor & Francis
Hyperuricemia and angiotensin II (Ang II) may have a pathogenetic role in the development
of hypertension and atherosclerosis as well as cardiovascular disease (CVD) and its …

Effect of Thyrotropin on Osteopontin, Integrin αvβ3, and VCAM-1 in the Endothelium via Activation of Akt

Y Yan, F Jiang, Y Lai, H Wang, A Liu, C Wang… - International Journal of …, 2016 - mdpi.com
Numerous epidemiological studies have shown that subclinical hypothyroidism (SCH) can
impair endothelial function and cause dyslipidemia. Studies have evaluated the effects of …