The role of chemokines in recruitment of immune cells to the artery wall and adipose tissue

BK Surmi, AH Hasty - Vascular pharmacology, 2010 - Elsevier
The role of the immune system is to recognize pathogens, tumor cells or dead cells and to
react with a very specific and localized response. By taking advantage of a highly …

The immune response in atherosclerosis: a double-edged sword

GK Hansson, P Libby - Nature reviews immunology, 2006 - nature.com
Immune responses participate in every phase of atherosclerosis. There is increasing
evidence that both adaptive and innate immunity tightly regulate atherogenesis. Although …

Inflammation and immune response in atherosclerosis

GK Hansson - Current atherosclerosis reports, 1999 - Springer
Atherosclerosis is an inflammatory disease with a significant autoimmune component.
Studies using transgenic murine models have clarified that recruitment of mononuclear …

Inflammatory mediators in atherosclerotic vascular remodeling

BR Evans, A Yerly, EPC van der Vorst… - Frontiers in …, 2022 - frontiersin.org
Atherosclerotic vascular disease remains the most common cause of ischemia, myocardial
infarction, and stroke. Vascular function is determined by structural and functional properties …

New insights into the role of inflammation in the pathogenesis of atherosclerosis

MY Wu, CJ Li, MF Hou, PY Chu - International journal of molecular …, 2017 - mdpi.com
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of
lipids, smooth muscle cell proliferation, cell apoptosis, necrosis, fibrosis, and local …

T cells in atherogenesis: for better or for worse?

AKL Robertson, GK Hansson - Arteriosclerosis, thrombosis, and …, 2006 - Am Heart Assoc
The idea that atherosclerosis is an inflammatory disease is no longer controversial. Instead,
much of the current research is now focused on understanding what drives this inflammation …

Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition

A Munjal, R Khandia - Advances in protein chemistry and structural biology, 2020 - Elsevier
The term atherosclerosis refers to the condition of deposition of lipids and other substances
in and on the artery walls, called as plaque that restricts the normal blood flow. The plaque …

Hegemony of inflammation in atherosclerosis and coronary artery disease

A Attiq, S Afzal, W Ahmad, M Kandeel - European Journal of Pharmacology, 2024 - Elsevier
Inflammation drives coronary artery disease and atherosclerosis implications. Lipoprotein
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …

Differential role of monocyte subsets in atherosclerosis

M Hristov, C Weber - Thrombosis and haemostasis, 2011 - thieme-connect.com
Endothelial dysfunction and inflammation of the arterial wall continuously drive the
development of atherosclerosis. Details regarding the sequential involvement of different …

Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies

R Klingenberg, GK Hansson - European heart journal, 2009 - academic.oup.com
Atherosclerosis constitutes the underlying disease to the clinical manifestations of
myocardial infarction, stroke, and gangrene. Despite the success of statins, prevention of …