Joint instability and cartilage trauma have been previously studied and identified as key
mediators in the development of posttraumatic osteoarthritis (PTOA). The purpose of this …

Joint injury is the predominant risk factor for post‐traumatic osteoarthritis development
(PTOA). Several non‐invasive mouse models mimicking human PTOA investigate molecular …

We investigated the spectrum of lesions characteristic of post-traumatic osteoarthritis (PTOA)
across the knee joint in response to mechanical injury. We hypothesized that alteration in …

OBJECTIVE: Post-traumatic osteoarthritis (PTOA) is a common consequence of traumatic
joint injury, with 50% of anterior cruciate ligament (ACL) rupture patients developing PTOA …

Objective Post-traumatic osteoarthritis (PTOA) is commonly studied using animal models.
Surgical ACL transection is an established model, but noninvasive models may mimic …

Post‐traumatic osteoarthritis (PTOA) is a common long‐term consequence of joint injuries
such as anterior cruciate ligament (ACL) rupture. In this study we used a tibial compression …

Osteoarthritis (OA) is a leading cause of disability worldwide. We hypothesized that
inflammation following isolated intra‐articular bone injury can stimulate post‐traumatic OA …

Translational models of posttraumatic osteoarthritis (PTOA) that accurately represent clinical
pathology need to be developed. This study assessed a novel canine model for PTOA using …

Animal models of osteoarthritis (OA) are essential tools for investigating the development of
the disease on a more rapid timeline than human OA. Mice are particularly useful due to the …

Post‐traumatic osteoarthritis (PTOA) is defined by its development after joint injury. Factors
contributing to the risk of PTOA occurring, the rate of progression, and degree of associated …