Lp (a) concentration and apo (a) isoform size. Relation to the presence of coronary artery disease in familial hypercholesterolemia.

JF Bowden, PH Pritchard, JS Hill… - … and Thrombosis: A …, 1994 - Am Heart Assoc
We studied the relation between the concentration of lipoprotein (a)[Lp (a)] in plasma,
apolipoprotein (a)[apo (a)] phenotype, and the clinical expression of coronary artery disease …

Apo (a) isoforms predict risk for coronary heart disease. A study in six populations.

C Sandholzer, N Saha, JD Kark, A Rees… - … and thrombosis: a …, 1992 - Am Heart Assoc
Elevated concentrations of lipoprotein (a)(Lp [a]) in plasma are associated with premature
coronary heart disease (CHD). Lp (a) levels are largely determined by alleles at the …

Studies on apolipoprotein (a) phenotypes. Part 2. Phenotype frequencies and Lp (a) concentrations in different phenotypes in patients with angiographically defined …

A Abe, A Noma, YJ Lee, H Yamaguchi - Atherosclerosis, 1992 - Elsevier
In the present paper, we have evaluated serum Lp (a) concentrations, the frequencies of Lp
(a) phenotypes and alleles and the association between the Lp (a) phenotypes and serum …

Coronary artery disease is associated with increased lipoprotein (a) concentrations independent of the size of circulating apolipoprotein (a) isoforms.

M Farrer, FL Game, CJ Albers, HA Neil… - … and Thrombosis: A …, 1994 - Am Heart Assoc
Lipoprotein (a)[Lp (a)] concentration and apolipoprotein (a)[apo (a)] isoforms (identified by
sodium dodecyl sulfate-polyacrylamide gel electrophoresis [SDS-PAGE] and Western …

Plasma lipoprotein (a) concentration in familial hypercholesterolemic patients without coronary artery disease

G Ghiselli, A Gaddi, G Barozzi, A Ciarrocchi… - Metabolism, 1992 - Elsevier
Familial Hypercholesterolemia (FH) is a condition characterized by markedly elevated blood
cholesterol, low-density lipoproteins (LDL), and apolipoprotein B-100 (apo B). The …

Relation of serum lipoprotein (a) concentration and apolipoprotein (a) phenotype to coronary heart disease in patients with familial hypercholesterolemia

M Seed, F Hoppichler, D Reaveley… - … England Journal of …, 1990 - Mass Medical Soc
Familial hypercholesterolemia carries a marked increase in the risk of coronary heart
disease (CHD), but there is considerable variation between individuals in susceptibility to …

Lipoprotein (a) concentrations and phenotypes in controls and patients with hypercholesterolemia or hypertriglyceridemia

MM Ritter, HC Geiss, WO Richter, P Schwandt - Metabolism, 1994 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] concentrations are known to be stable under various dietary
and drug regimens. Little is known about the influence of hyperlipoproteinemia on Lp (a) …

Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus.

CA DeMeester, X Bu, RJ Gray, AJ Lusis… - American journal of …, 1995 - ncbi.nlm.nih.gov
Abstract Lipoprotein (a)(Lp [a]) is a cholesterol-rich lipoprotein resembling LDL but also
containing a large polypeptide designated apolipoprotein (a)(apo [a]). Its levels are highly …

Serum lipoprotein (a) in patients heterozygous for familial hypercholesterolemia, their relatives, and unrelated control populations.

AD Mbewu, D Bhatnagar, PN Durrington… - … and Thrombosis: A …, 1991 - Am Heart Assoc
Serum lipoprotein (a)(Lp [a]) levels were significantly higher in 89 patients with
heterozygous familial hypercholesterolemia (FH)(geometric mean, 22.7 mg/dl) than in 109 …

Lipoprotein (a) in homozygous familial hypercholesterolemia

HG Kraft, A Lingenhel, FJ Raal… - … , and vascular biology, 2000 - Am Heart Assoc
Lipoprotein (a)[Lp (a)] is a quantitative genetic trait that in the general population is largely
controlled by 1 major locus—the locus for the apolipoprotein (a)[apo (a)] gene. Sibpair …