Deletion of chromosome bands 1 Iq22-q23 is one of the most common structural
chromosome alterations in chronic lymphocytic leukemia (CLL) and mantle cell lymphoma …

Background Recently, we clarified at the molecular level novel chromosomal translocation t
(14; 14)(q11; q32) in a case of Sézary syndrome, which caused a rearrangement from …

Deletion of 11q22–q23 is associated with an aggressive course of B-cell chronic
lymphocytic leukaemia (B-CLL). Since only in a subset of these cases biallelic inactivation of …

Loss of genomic material from chromosomal band 13q14. 3 is the most common genetic
imbalance in B-cell chronic lymphocytic leukemia (B-CLL) and mantle cell lymphoma …

The technology of array comparative genomic hybridization (array-CGH/aCGH) enabled the
identification of novel genomic aberrations in chronic lymphocytic leukemia (CLL) including …

Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with regard to its clinical
course. The limitations of the methods currently available for prognostic assessment in CLL …

To determine the prognostic impact of de novo deletion 17p13. 1 (17p–) in previously
untreated chronic lymphocytic leukemia (CLL) patients, we prospectively studied the …

We used BAC array-based CGH to detect genomic imbalances in 187 CLL cases.
Submicroscopic deletions of chromosome 22q11 were observed in 28 cases (15%), and the …

Recently, the PTEN/MMAC1 gene encoding a protein phosphatase (PP) and the PPP2R1B
gene encoding a regulatory subunit of PP2A have been identified as being genetically …

We describe unusual clinical and cytogenetic findings of a 29-year-old female with a
Philadelphia chromosome (Ph)-positive chronic myeloid leukemia (CML), who showed a …