In 1964, acetate was introduced into dialysis therapy as a substitute for bicarbonate to
overcome the technical problem of precipitation of carbonate salts in the bath (Mion et al …

IN the early 1960s hemodialysis was performed with bicarbonate in the dialysate. Although
this was quite effective in restoring the serum bicarbonate to normal, it posed a practical …

Effects of acetate and bicarbonate dialysate in stable chronic dialysis patients. The effects of
acetate and bicarbonate dialysate on the biochemical and clinical parameters of 16 stable …

Eight stable center dialysis patients completed four, 10-week study periods in which either
acetate or bicarbonate dialysis was used, each with high or low sodium concentration …

Acetate is used as the source of bicarbonate during hemodialysis. The purpose of the
present experiments was to determine the metabolic consequences of acute acetate …

Eleven stable hemodialysis patients were treated with acetate dialysate, then changed to
bicarbonate dialysate at three different concentrations. Blood was drawn from the arterial …

The utilization of acetate and its effects on acid-base balance and on free fatty acid
metabolism were investigated during regular hemodialysis (HD). Fourteen patients with …

Metabolic acidosis is observed in 60% to 80% of patients with severe renal failure at the time
of ini-tiation of chronic dialysis (1, 2). Because acid production is normal, the acidosis has …

The purpose of our study was to investigate the feasibility of using lactate as a complete or
partial substitute for acetate in hemodialysis solutions. Six patients, each serving as his own …

Early dialysis systems used bicarbonate to correct the acidosis ofrenal failure, and this
required carbon dioxide to be bubbled continuously through the dialysis fluid to prevent a …