[HTML][HTML] Approaches for incorporating environmental mixtures as mediators in mediation analysis

A Bellavia, T James-Todd, PL Williams - Environment international, 2019 - Elsevier
Mediation analysis offers an essential and rapidly expanding tool in environmental health
studies to investigate the contribution of environmental factors towards observed …

Multiple mediators approach to study environmental chemicals as determinants of health disparities

A Bellavia, AR Zota, L Valeri… - Environmental …, 2018 - journals.lww.com
A major goal of health disparities research is to identify and intervene upon modifiable risk
factors that help explain the observed associations between social factors and adverse …

Challenges raised by mediation analysis in a high-dimension setting

MGB Blum, L Valeri, O François, S Cadiou… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Mediation analysis is used in epidemiology to identify pathways through which
exposures influence health. The advent of high-throughput (omics) technologies gives …

Statistical approaches for assessing health effects of environmental chemical mixtures in epidemiology: lessons from an innovative workshop

KW Taylor, BR Joubert, JM Braun… - Environmental …, 2016 - ehp.niehs.nih.gov
Quantifying the impact of exposure to environmental chemical mixtures is important for
identifying risk factors for diseases and developing more targeted public health …

Evaluating chemical mixtures in epidemiological studies to inform regulatory decisions

DA Savitz, AM Hattersley - Environmental health perspectives, 2023 - ehp.niehs.nih.gov
Background: Epidemiological studies are increasingly going beyond the evaluation of health
effects of individual chemicals to consider chemical mixtures. To our knowledge, the …

Complex mixtures, complex analyses: an emphasis on interpretable results

EA Gibson, J Goldsmith… - Current environmental …, 2019 - Springer
Abstract Purpose of Review The purpose of this review is to outline the main questions in
environmental mixtures research and provide a non-technical explanation of novel or …

Bias amplification in epidemiologic analysis of exposure to mixtures

MG Weisskopf, RM Seals… - Environmental health …, 2018 - ehp.niehs.nih.gov
Background: The analysis of health effects of exposure to mixtures is a critically important
issue in human epidemiology, and increasing effort is being devoted to developing methods …

Bayesian kernel machine regression‐causal mediation analysis

KL Devick, JF Bobb, M Mazumdar… - Statistics in …, 2022 - Wiley Online Library
Greater understanding of the pathways through which an environmental mixture operates is
important to design effective interventions. We present new methodology to estimate natural …

Mediation analysis with multiple mediators

T VanderWeele, S Vansteelandt - Epidemiologic methods, 2014 - degruyter.com
Recent advances in the causal inference literature on mediation have extended traditional
approaches to direct and indirect effects to settings that allow for interactions and non …

Statistical strategies for constructing health risk models with multiple pollutants and their interactions: possible choices and comparisons

Z Sun, Y Tao, S Li, KK Ferguson, JD Meeker… - Environmental …, 2013 - Springer
Background As public awareness of consequences of environmental exposures has grown,
estimating the adverse health effects due to simultaneous exposure to multiple pollutants is …