Background The effects of cyclosporine (Cs), a fungal cyclic polypeptide with potent
immunosuppressive activity, on fertility have assumed greater significance with the …

Ribavirin (1-β-d-ribofuranosyl-1, 2, 4, triazole-3 carboxamide) is a broad-spectrum antiviral
drug. This study was aimed to investigate the mutagenicity of ribavirin on germ cells by …

Background: Propoxur is a carbamate pesticide widely used in crop and foodstuff protection.
They are known to cause a wide variety of symptoms in animals. Methods: Twenty four …

A new male contraceptive given the name RISUG®(an acronym for reversible inhibition of
sperm under guidance) and presently undergoing advanced clinical trials has been …

Background: It is known that vanadyl compounds are capable of alleviating hyperglycemia
in streptozotocin induced diabetic rats. Objective: To examine the effect of vanadyl sulphate …

Objective Gore‐tex bags were placed over sheep ovaries and tissue reaction was assessed.
Setting The study was conducted at The University of Queensland under the supervision of …

Although alternative test methods based on the 3Rs (Replacement, Reduction, Refinement)
are being developed to replace animal testing in reproductive and developmental …

Background: SETARUD (IMODTM) is a new herbal drug that has demonstrated immune
modulating activity in preliminary investigations. The aim of this study was to evaluate the …

Objective: To investigate the in vivomutagenic effects of ribavirin in mice. Methods: Mice
were injected (ip) 20, 100, or 200 mg/kg ribavirin (single exposure) for bone marrow …