Label-Free SERS of Urine Components: A Powerful Tool for Discriminating Renal Cell Carcinoma through Multivariate Analysis and Machine Learning Techniques

BA Buhas, V Toma, JB Beauval, I Andras… - International Journal of …, 2024 - mdpi.com
The advent of Surface-Enhanced Raman Scattering (SERS) has enabled the exploration
and detection of small molecules, particularly in biological fluids such as serum, blood …

High-accuracy renal cell carcinoma discrimination through label-free SERS of Blood serum and multivariate analysis

BA Buhas, V Toma, N Crisan, G Ploussard, TA Maghiar… - Biosensors, 2023 - mdpi.com
Renal cell carcinoma (RCC) represents the sixth most frequently diagnosed cancer in men
and is asymptomatic, being detected mostly incidentally. The apparition of symptoms …

Surface-enhanced Raman scattering-based detection of cancerous renal cells

S Mert, M Culha - Applied spectroscopy, 2014 - journals.sagepub.com
Surface-enhanced Raman scattering (SERS) is used for the differentiation of human kidney
adenocarcinoma, human kidney carcinoma, and non-cancerous human kidney embryonic …

SERS liquid biopsy profiling of serum for the diagnosis of kidney cancer

T Moisoiu, SD Iancu, D Burghelea, MP Dragomir… - Biomedicines, 2022 - mdpi.com
Renal cancer (RC) represents 3% of all cancers, with a 2% annual increase in incidence
worldwide, opening the discussion about the need for screening. However, no established …

Non-invasive disease diagnosis using surface-enhanced Raman spectroscopy of urine and saliva

L Ma, Z Zhang, X Li - Applied Spectroscopy Reviews, 2020 - Taylor & Francis
Due to the high sensitivity, specificity, efficiency and cost-effectiveness, surface-enhanced
Raman spectroscopy (SERS) has been extensively used for the detection and evaluation of …

Label-free detection of bladder cancer and kidney cancer plasma based on SERS and multivariate statistical algorithm

X Bai, J Lin, X Wu, Y Lin, X Zhao, W Du, J Gao… - … Acta Part A: Molecular …, 2022 - Elsevier
In this study, we mainly aimed to investigate the diagnostic potential of surface-enhanced
Raman spectroscopy for bladder cancer and kidney cancer which are the most common …

Label-free detection of multiple genitourinary cancers from urine by surface-enhanced Raman spectroscopy

X Cui, T Liu, X Xu, Z Zhao, Y Tian, Y Zhao… - … Acta Part A: Molecular …, 2020 - Elsevier
Detecting cancers through testing biological fluids, namely,“liquid biopsy”, is noninvasive
and shows great promise in cancer diagnosis, surveillance and screening. Many …

Combining SERS analysis of serum with PSA levels for improving the detection of prostate cancer

A Stefancu, V Moisoiu, R Couti, I Andras, R Rahota… - …, 2018 - Taylor & Francis
Aim: Previous studies regarding surface-enhanced Raman scattering (SERS) of serum have
shown promising initial results in discriminating prostate cancer, a strategy which could …

SERS-based differential diagnosis between multiple solid malignancies: Breast, colorectal, lung, ovarian and oral cancer

V Moisoiu, A Stefancu, D Gulei, R Boitor… - International journal …, 2019 - Taylor & Francis
Purpose Surface-enhanced Raman scattering (SERS) spectroscopy on serum and other
biofluids for cancer diagnosis represents an emerging field, which has shown promising …

Characterization and noninvasive diagnosis of bladder cancer with serum surface enhanced Raman spectroscopy and genetic algorithms

S Li, L Li, Q Zeng, Y Zhang, Z Guo, Z Liu, M Jin, C Su… - Scientific reports, 2015 - nature.com
This study aims to characterize and classify serum surface-enhanced Raman spectroscopy
(SERS) spectra between bladder cancer patients and normal volunteers by genetic …