BACKGROUND: Social interaction can serve as a natural reward that attenuates drug
reward in rats; however, it is unknown if age or housing conditions alter the choice between …

A recent thrust in drug abuse research is the influence of social interactions on drug effects.
Therefore, the present study examined conditioned place preference (CPP) as a model for …

Interaction with social peers may increase rates of drug self-administration, but a recent
study from our laboratory showed that social interaction may serve as a type of alternative …

Rationale Among human adolescents, drug use is substantially influenced by the attitudes
and behaviors of peers. Social factors also affect the drug-seeking behaviors of laboratory …

Adolescence is a period of enhanced sensitivity to social influences and vulnerability to drug
abuse. Social reward in adolescent rats has been demonstrated with the conditioned place …

A main challenge in the therapy of drug dependent individuals is to help them reactivate
interest in non-drug-associated activities. We previously developed a rat experimental …

In this study, we investigated behavioral factors underlying conditioned place preference
(CPP) induced by social interaction in adolescent rats. We found that the magnitude of …

Rationale Smoking typically begins during adolescence and is largely reinforced by social
cues. During adolescence in rats, sensitivity to both social cues and drugs of abuse is …

Rationale Drug addiction is a multifactorial disorder resulting from an interaction between
genetic and environmental factors, and negative and positive environmental conditions may …

Positive social interaction could play an essential role in switching the preference of the
substance dependent individual away from drug related activities. We have previously …