Rationale and objective Social factors play a critical role in drug addiction. We recently
showed that rats will abstain from methamphetamine, cocaine, heroin, and remifentanil self …

In rodents, a conditioned place preference (CPP) can be induced by morphine. In the current
study, we designed a biased place conditioning paradigm to test the rewarding effects of …

Cocaine use disorder occurs in an environment where cocaine and other nondrug
commodities are concurrently available. Preclinical drug-vs-nondrug choice procedures are …

It is widely accepted that early environmental influences may affect the behaviour of the
adult animal and the responsivity to psychotropic drugs. Isolation rearing is an important …

Background A main challenge in the therapy of drug dependent individuals is to help them
reactivate interest in non-drug-associated activities. Among these activities, social …

We previously reported that chronic social stress (SS) in adolescence, but not in adulthood,
increased the locomotor‐activating effects of nicotine in females, and not males, when tested …

Abstract Forty-eight male Sprague-Dawley rats were conditioned with either water or 4 g/kg
ethanol in a standard drug place-learning task. In addition to the drug treatment, the …

Busse and Riley [Biol. Psychiatry 26 (2002) 1373] have recently reported that alcohol dose
dependently attenuated cocaine-induced place preferences. Although the mechanism for …

Whether social isolation of adult rats under standard laboratory conditions produces
significant long-term alterations in behavior and physiology is unclear. In the present study …

Rats learn to prefer a place that has been paired with the rewarding effect of amphetamine.
Since amphetamine is also known to produce an aversive effect, called here sickness …