Neuropsychiatric effects and type of IFN-α in chronic hepatitis C

M Malaguarnera, A Laurino, I Di Fazio… - Journal of Interferon & …, 2001 - liebertpub.com
Chronic hepatitis is often associated with neuropsychiatric disorders. Interferon (IFN) is the
drug most widely used to treat this disease, and its side effects, such as depression, often …

Depression induced by treatment with interferon-alpha in patients affected by hepatitis C virus

S Bonaccorso, V Marino, M Biondi, F Grimaldi… - Journal of affective …, 2002 - Elsevier
Background: Several studies found a high incidence rate of neuro-psychiatric complications
during long-term therapy with interferon alpha (IFNα), eg slowness, severe fatigue …

[HTML][HTML] Neuropsychiatric side-effects of interferon alfa therapy for hepatitis C and their management: a review

YR Al-Huthail - Saudi Journal of Gastroenterology, 2006 - journals.lww.com
Background: Interferon-Alfa (IFN-α) has been the mainstay of treatment for chronic hepatitis
C. It has the potential to alter the course of chronic hepatitis C and prevent complications …

Interferon alpha-induced depression in chronic hepatitis C patients: comparison between different types of interferon alpha

M Malaguarnera, I Di Fazio, S Restuccia… - …, 1998 - karger.com
IFN alpha treatment is able to produce dose-related side effects, such as depression, in the
central nervous system. We assessed the effects on depression of four different types of IFN …

Immunotherapy with interferon-alpha in patients affected by chronic hepatitis C induces an intercorrelated stimulation of the cytokine network and an increase in …

S Bonaccorso, A Puzella, V Marino, M Pasquini… - Psychiatry …, 2001 - Elsevier
Immunotherapy with interferon-alpha (IFNα) may induce depressive symptoms, anxiety and
major depression when administered for at least 1–3 months at a dose of 3–10 MUI daily …

Psychiatric symptoms related to interferon therapy for chronic hepatitis C: clinical features and prognosis

S Hosoda, H Takimura, M Shibayama… - Psychiatry and …, 2000 - Wiley Online Library
Psychiatric symptoms during interferon (IFN) therapy for viral hepatitis have been a crucial
problem in consultation‐liaison psychiatry. However, there have been few studies on …

Association of interferon-α-induced depression and improved treatment response in patients with hepatitis C

JM Loftis, RE Socherman, CD Howell, AJ Whitehead… - Neuroscience …, 2004 - Elsevier
Thirty-nine patients with hepatitis C viral infection on interferon-α (IFN-α) therapy were
monitored weekly using the Beck Depression Inventory (BDI). Thirteen of thirty-nine patients …

Mood, cognition and EEG changes during interferon α (alpha-IFN) treatment for chronic hepatitis C

P Amodio, EN De Toni, L Cavalletto, D Mapelli… - Journal of affective …, 2005 - Elsevier
BACKGROUND: This study is aim to investigate concurrent long-term psychiatric, cognitive
and neurophysiological measures of α-IFN neurotoxicity in the treatment of chronic viral …

Depression during interferon therapy in chronic hepatitis C patients--a prospective study

T Otsubo, H Miyaoka, K Kamijima, M Onuki… - … zasshi= Psychiatria et …, 1997 - europepmc.org
The number of patients treated with interferon (IFN) has increased markedly in Japan since
1992, when the Health and Welfare Ministry approved the use of IFN for treating chronic …

A prospective study of the incidence and open-label treatment of interferon-induced major depressive disorder in patients with hepatitis C

P Hauser, J Khosla, H Aurora, J Laurin, MA Kling… - Molecular …, 2002 - nature.com
Interferon (IFN) therapy has been associated with the development of Major Depressive
Disorder (MDD) when given to patients with hepatitis C (HCV). The incidence, time course …