Exposure to air pollutants has been correlated with an increase in the severity of asthma and
in the exacerbation of pre-existing asthma. However, whether or not environmental pollution …

In recent decades, clinicians and scientists have witnessed a significant increase in the
prevalence of allergic rhinitis and asthma. The factors underlying this phenomenon are …

(PM) and increasing respiratory mortality and morbidity [1]. In western countries, exhausts
from diesel and gasoline vehicles constitute a major portion of PM and have been suspected …

Host responses to DEPs are regulated by a balance between antioxidants and
proinflammatory responses. DEP-induced oxidants play a key role in proinflammatory …

Diesel exhaust and its particles (DEP) have been under scrutiny for health effects in
humans. In the development of these effects inflammation is regarded as a key process …

Inflammation after diesel exhaust and DEP exposure is evident at higher concentrations
only; there appears to be a threshold dose for DEPs approximating 300 μg/m 3. The lack of a …

Background Epidemiologic studies have reported an association between diesel exhaust
particle (DEP) exposure, allergic sensitization, and childhood wheezing, although the …

Prevalence of asthma is increasing in westernized countries. Epidemiological studies
showed the impact of traffic pollution on the triggering of asthma symptoms and …

Epidemiological studies have shown that particulate air pollutants, such as diesel exhaust
particles (DEPs) are implicated in the increased incidence of allergic airway disorders. DEPs …

BACKGROUND: Diesel emission particulates (DEP) exert effects on the immune system and
act as an adjuvant which enhances allergic inflammation. Animal and human models have …