Responses of cultured human airways epithelial cells treated with diesel exhaust extracts will vary with the engine load

MC Madden, LA Dailey, JG Stonehuerner… - Journal of Toxicology …, 2003 - Taylor & Francis
Numerous epidemiological studies have associated levels of ambient particles with mortality
and morbidity, including increased asthma symptoms and pul-monary infections (Dockery et …

Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system

AE Nel, D Diaz-Sanchez, D Ng, T Hiura… - Journal of Allergy and …, 1998 - Elsevier
There is growing evidence that fossil fuel combustion products act as adjuvants in the
immune system and may lead to enhancement of allergic inflammation. Through this …

Diesel exhaust particles induce NF-κB activation in human bronchial epithelial cells in vitro: importance in cytokine transcription

H Takizawa, T Ohtoshi, S Kawasaki… - The Journal of …, 1999 - journals.aai.org
Fine particles derived from diesel engines (diesel exhaust particles, DEP) have attracted
attention, since their density in industrial countries seems related to the increased …

[引用][C] Diesel exhaust particles and respiratory allergy

AJ Frew, SS Salvi - Clinical & Experimental Allergy, 1997 - Wiley Online Library
Air pollution is a subject of increasing concern throughout the developed and developing
worlds. Historically, most concern has been directed towards acid aerosols and black …

Physiological and inflammatory responses in an anthropomorphically relevant model of acute diesel exhaust particle exposure are sex and dose-dependent

CE Boylen, PD Sly, GR Zosky… - Inhalation toxicology, 2011 - Taylor & Francis
Context: Diesel exhaust particles (DEP) are an important contributor to suspended
particulate matter (PM) in urban areas. While epidemiological evidence exists for a sex …

The influence of diesel exhaust particles on mononuclear phagocytic cell-derived cytokines: IL-10, TGF-β and IL-1β

KA Pacheco, M Tarkowski, C Sterritt… - Clinical & …, 2001 - academic.oup.com
Diesel exhaust particles (DEP) are known to modulate the production of cytokines
associated with acute and chronic respiratory symptoms and allergic respiratory disease …

Pulmonary exposure to diesel exhaust particles induces airway inflammation and cytokine expression in NC/Nga mice

K Inoue, H Takano, R Yanagisawa, T Ichinose… - Archives of …, 2005 - Springer
Although several studies have reported that diesel exhaust particles (DEP) affect
cardiorespiratory health in animals and humans, the effect of DEP on animal models with …

Cellular basis of the role of diesel exhaust particles in inducing Th2-dominant response

T Ohtani, S Nakagawa, M Kurosawa… - The Journal of …, 2005 - journals.aai.org
There is growing evidence that diesel exhaust particles (DEP) can induce allergic diseases
with increased IgE production and preferential activation of Th2 cells. To clarify the cellular …

Exacerbation of allergic inflammation in mice exposed to diesel exhaust particles prior to viral infection

I Jaspers, PA Sheridan, W Zhang, LE Brighton… - Particle and fibre …, 2009 - Springer
Background Viral infections and exposure to oxidant air pollutants are two of the most
important inducers of asthma exacerbation. Our previous studies have demonstrated that …

Pro-oxidative diesel exhaust particle chemicals inhibit LPS-induced dendritic cell responses involved in T-helper differentiation

RCF Chan, M Wang, N Li, Y Yanagawa, K Onoé… - Journal of allergy and …, 2006 - Elsevier
BACKGROUND: Epidemiologic studies show that exposure to ambient particulate matter
leads to asthma exacerbation. Diesel exhaust particles (DEPs), a model pollutant, act as an …