Diesel exhaust particles stimulate human airway epithelial cells to produce cytokines relevant to airway inflammation in vitro

T Ohtoshi, H Takizawa, H Okazaki, S Kawasaki… - Journal of Allergy and …, 1998 - Elsevier
Background: Epidemiologic and experimental studies suggest that air pollution such as
diesel exhaust particles (DEPs), one of the important air pollutants, may play a role in the …

Differential proinflammatory responses induced by diesel exhaust particles with contrasting PAH and metal content

AI Totlandsdal, M Låg, E Lilleaas… - Environmental …, 2015 - Wiley Online Library
Exposure to diesel engine exhaust particles (DEPs), representing a complex and variable
mixture of components, has been linked with cellular production and release of several …

Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans

AF Behndig, IS Mudway, JL Brown… - European …, 2006 - Eur Respiratory Soc
Pulmonary cells exposed to diesel exhaust (DE) particles in vitro respond in a hierarchical
fashion with protective antioxidant responses predominating at low doses and inflammation …

Effects of diesel exposure on lung function and inflammation biomarkers from airway and peripheral blood of healthy volunteers in a chamber study

Y Xu, L Barregard, J Nielsen, A Gudmundsson… - Particle and fibre …, 2013 - Springer
Background Exposure to diesel exhaust causes inflammatory responses. Previous
controlled exposure studies at a concentration of 300 μg/m 3 of diesel exhaust particles …

The Effect of Diesel Exhaust Particles on Cell Function and Release of Inflammatory Mediators from Human Bronchial Epithelial Cells In Vitro

H Bayram, JL Devalia, RJ Sapsford… - American journal of …, 1998 - atsjournals.org
Animal studies have reported that diesel exhaust particles (DEP), which constitute an
important fraction of particulate air pollution, lead to inflammation and/or damage of the …

Chemical characterization and in vitro toxicity of diesel exhaust particulate matter generated under varying conditions

JR Fox, DP Cox, BE Drury, TR Gould… - Air Quality, Atmosphere …, 2015 - Springer
Epidemiologic studies have linked diesel exhaust (DE) to cardiovascular and respiratory
morbidity and mortality, as well as lung cancer. DE composition is known to vary with many …

Subchronic effects of nasally instilled diesel exhaust particulates on the nasal and airway epithelia in mice

K Yoshizaki, JM Brito, AC Toledo… - Inhalation …, 2010 - Taylor & Francis
Diesel exhaust is the major source of ultrafine particles released during traffic-related
pollution. Subjects with chronic respiratory diseases are at greater risk for exacerbations …

In vitro pulmonary and vascular effects induced by different diesel exhaust particles

R Bengalli, A Zerboni, S Marchetti, E Longhin, M Priola… - Toxicology letters, 2019 - Elsevier
Diesel exhaust particles (DEP) are responsible for both respiratory and cardiovascular
effects. However many questions are still unravelled and the mechanisms behind the health …

Route of exposure alters inflammation and lung function responses to diesel exhaust

AN Larcombe, JA Phan, A Kicic, KL Perks… - Inhalation …, 2014 - Taylor & Francis
Context: Mice are commonly used in studies investigating the effects of diesel exhaust
exposure on respiratory health. A plethora of studies in this field has resulted in a range of …

Health effects of diesel emissions

WKC Morgan, RB Reger… - The Annals of occupational …, 1997 - academic.oup.com
We have reviewed the literature relating to the health effects of diesel emissions with
particular reference to acute and chronic morbidity and to carcinogenicity. It is apparent that …