Route of exposure alters inflammation and lung function responses to diesel exhaust

AN Larcombe, JA Phan, A Kicic, KL Perks… - Inhalation …, 2014 - Taylor & Francis
Context: Mice are commonly used in studies investigating the effects of diesel exhaust
exposure on respiratory health. A plethora of studies in this field has resulted in a range of …

Health effects of diesel emissions

WKC Morgan, RB Reger… - The Annals of occupational …, 1997 - academic.oup.com
We have reviewed the literature relating to the health effects of diesel emissions with
particular reference to acute and chronic morbidity and to carcinogenicity. It is apparent that …

Diesel particulate material binds and concentrates a proinflammatory cytokine that causes neutrophil migration

JC Seagrave, C Knall, JD McDonald… - Inhalation …, 2004 - Taylor & Francis
Exposure to combustion emissions is associated with adverse health effects, but the
properties of the emissions that induce these effects are not fully understood. To examine …

Influence of inflammation and nitric oxide upon platelet aggregation following deposition of diesel exhaust particles in the airways

E Smyth, A Solomon, MA Birrell… - British journal of …, 2017 - Wiley Online Library
Background and Purpose Exposure to nanoparticulate pollution has been implicated in
platelet‐driven thrombotic events such as myocardial infarction. Inflammation and …

Diesel exhaust particles induced release of interleukin 6 and 8 by (primed) human bronchial epithelial cells (BEAS 2B) in vitro

PA Steerenberg, JAJ Zonnenberg… - Experimental lung …, 1998 - Taylor & Francis
Several epidemiological studies have recently shown associations of increased premature
mortality rates with ambient paniculate air pollution. Diesel exhaust particles (DEP) may …

IL33 contributes to diesel pollution‐mediated increase in experimental asthma severity

EB Brandt, PE Bolcas, BP Ruff, GK Khurana Hershey - Allergy, 2020 - Wiley Online Library
Background Exposure to traffic pollution, notably diesel exhaust particles (DEP), increases
risk for asthma and asthma exacerbations. The contribution of cytokines generated by …

[HTML][HTML] Effects of diesel exhaust particle exposure on a murine model of asthma due to soybean

D Alvarez-Simon, X Munoz, S Gomez-Olles… - PLoS …, 2017 - journals.plos.org
Background Exposure to soybean allergens has been linked to asthma outbreaks. Exposure
to diesel exhaust particles (DEP) has been associated with an increase in the risk of asthma …

Chemical constituents of diesel exhaust particles induce IL-4 production and histamine release by human basophils

G Devouassoux, A Saxon, DD Metcalfe… - Journal of Allergy and …, 2002 - Elsevier
Background: An epidemiologic relationship between airway allergic diseases and exposure
to atmospheric pollutants has been demonstrated and suggested to be one factor in the …

Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in mice

H Takano, T Yoshikawa, T Ichinose… - American Journal of …, 1997 - atsjournals.org
Previous experimental studies have suggested that nasal instillation of diesel exhaust
particles (DEP) can enhance nasal IgE response and cytokine production. However, there is …

Interplay of air pollution and asthma immunopathogenesis: a focused review of diesel exhaust and ozone

NE Alexis, C Carlsten - International immunopharmacology, 2014 - Elsevier
Controlled human exposure experiments with diesel exhaust particles (DEPs) and ozone
serve to illustrate the important role pollutants play in modulating both allergic mechanisms …