Harnessing the immune system for the treatment of non–small-cell lung cancer

JR Brahmer - Journal of Clinical Oncology, 2013 - ascopubs.org
Over the last several years, new therapeutic targets have emerged in immunotherapy,
particularly the immune checkpoint pathways. Blocking inhibitory pathways via monoclonal …

Immunotherapy for lung cancer

A Steven, SA Fisher, BW Robinson - Respirology, 2016 - Wiley Online Library
Abstract Treatment of lung cancer remains a challenge, and lung cancer is still the leading
cause of cancer‐related mortality. Immunotherapy has previously failed in lung cancer but …

New strategies in lung cancer: translating immunotherapy into clinical practice

PM Forde, RJ Kelly, JR Brahmer - Clinical Cancer Research, 2014 - AACR
Recent breakthroughs in translating the early development of immunomodulatory antibodies
into the clinic, notably with the anti–cytotoxic T-lymphocyte antigen-4 antibody, ipilimumab …

[HTML][HTML] Immunotherapy in lung cancer

LC Villaruz, A Kalyan, H Zarour… - … lung cancer research, 2014 - ncbi.nlm.nih.gov
Immunotherapy has emerged in recent years as a promising therapeutic approach in lung
cancer. Two approaches are of particular interest: immune checkpoint inhibition, which aims …

Immunotherapy comes of age in lung cancer

P Khanna, N Blais, PO Gaudreau… - Clinical lung cancer, 2017 - Elsevier
Lung carcinoma is the leading cause of death by cancer worldwide. When possible, surgery
is the best treatment strategy for patients with non–small-cell lung cancer. However, even …

Immunotherapy in non-small cell lung cancer: Past, present, and future directions

SR Punekar, E Shum, CM Grello, SC Lau… - Frontiers in …, 2022 - frontiersin.org
Many decades in the making, immunotherapy has demonstrated its ability to produce
durable responses in several cancer types. In the last decade, immunotherapy has shown …

What Lies Within: Novel Strategies in Immunotherapy for Non‐Small Cell Lung Cancer

PM Forde, KA Reiss, AM Zeidan, JR Brahmer - The oncologist, 2013 - academic.oup.com
Introduction. Immunotherapy has become an increasingly important therapeutic strategy for
those with cancer, with phase III studies demonstrating survival advantages in melanoma …

New modalities of cancer treatment for NSCLC: focus on immunotherapy

M Davies - Cancer management and research, 2014 - Taylor & Francis
Recent advances in the understanding of immunology and antitumor immune responses
have led to the development of new immunotherapies, including vaccination approaches …

[HTML][HTML] Clinical trials integrating immunotherapy and radiation for non–small-cell lung cancer

ME Daly, AM Monjazeb, K Kelly - Journal of Thoracic Oncology, 2015 - Elsevier
Methods of harnessing the immune system to treat cancer have been investigated for
decades, but yielded little clinical progress. However, in recent years, novel drugs that allow …

[PDF][PDF] Immunotherapy for non-small-cell lung cancer: current status and future obstacles

JH Cho - Immune network, 2017 - synapse.koreamed.org
Lung cancer is one of the leading causes of death worldwide. There are 2 major subtypes of
lung cancer, non-small-cell lung cancer (NSCLC) and small-cell lung cancer (SCLC) …