Rational medicine use in neonates implies the prescription and administration of age-
appropriate drug formulations, selecting the most efficacious and safe dose, all based on …

The optimal evaluation and use of antibacterial agents that are very frequently prescribed in
neonates during various situations such as early-and late-onset invasive infections depend …

Antibiotics are often used in neonates despite the absence of relevant dosing information in
drug labels. For neonatal dosing, clinicians must extrapolate data from studies for adults and …

Antibiotics are invaluable in the management of neonatal infections. However, overuse or
misuse of antibiotics in neonates has been associated with adverse outcomes, including …

Due to complex maturational and physiological changes that characterize neonates and
affect their response to pharmacological treatments, neonatal pharmacology is different from …

Antibiotic stewardship aims to ensure that clinicians administer the right antibiotics, to the
right patients, for the right reasons. These principles are being widely applied in medical …

Purpose Incorrect dosage was the most common type of medication errors in neonate
patients. Different dosing recommendations from common reference sources may have …

The selection of the right antibiotic and right dose necessitates clinicians understand the
contribution of pharmacokinetic variability stemming from age‐related physiologic …

Antibiotic stewardship programmes aim to optimise antimicrobial use to prevent the
emergence of resistance species and protect patients from the side effects of unnecessary …

Dosing of antibiotics in neonates requires finding a delicate balance between maximal
efficacy and minimal toxicity. There is a lack of data on efficacy of currently used antibiotics …