Background An increase in airway caliber (airway distensibility) with lung inflation is
attenuated in COPD. Furthermore, some subjects have a decrease in airway caliber with …

Background CT scan measures of emphysema and airway disease have been correlated
with lung function in cohorts of subjects with a range of COPD severity. The contribution of …

Background In CT scans of smokers with COPD, the subsegmental airway wall area percent
(WA%) is greater and more strongly correlated with FEV 1% predicted than WA% obtained …

Background Chronic obstructive pulmonary disease (COPD) is characterized by airflow
limitation caused by emphysema and small airway narrowing. Quantitative evaluation of …

BACKGROUND: COPD patients have varying degrees of airways disease and emphysema.
CT scanning can differentiate these pathological subtypes. We evaluated airway dimensions …

Background: Chronic obstructive pulmonary disease (COPD) is characterised by the
presence of airflow limitation caused by loss of lung elasticity and/or airway narrowing. The …

There is limited knowledge on the relationship between diffusing capacity of the lung for
carbon monoxide (DLCO) and quantitative computed tomography (CT) measures of …

Objectives Chronic obstructive pulmonary disease (COPD) is characterized by variable
contributions of emphysema and airway disease on computed tomography (CT), and still …

Objective: It is not well known whether there is heterogeneity in the airway dimensions at
different anatomic locations in individual patients with COPD. The first objective was to …

Background COPD is a complex, heterogeneous disease characterised by progressive
development of airflow limitation. Spirometry provides little information about key aspects of …