Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis

JR Donnan, CA Grandy, E Chibrikov, CA Marra… - BMJ open, 2019 - bmjopen.bmj.com
Objective To estimate the association between the use of sodium glucose co-transporter-2
(SGLT2) inhibitors and postmarket harms as identified by drug regulatory agencies. Design …

Adverse events associated with sodium glucose co-transporter 2 inhibitors: an overview of quantitative systematic reviews

R Pelletier, K Ng, W Alkabbani… - … Advances in Drug …, 2021 - journals.sagepub.com
Background: Multiple published quantitative systematic reviews have reported on adverse
events associated with the use of sodium glucose co-transporter 2 (SGLT-2) inhibitors in …

Sodium–Glucose Co-Transporter 2 Inhibitors (SGLT2i) Exposure and Outcomes in Type 2 Diabetes: A Systematic Review of Population-Based Observational Studies

TM Caparrotta, AM Greenhalgh, K Osinski, RM Gifford… - Diabetes Therapy, 2021 - Springer
Introduction Sodium–glucose co-transporter 2 inhibitors (SGLT2is) are licensed for the
treatment of type 2 diabetes (T2D) and more recently for heart failure with or without …

A safety update on sodium glucose co‐transporter 2 inhibitors

D Fitchett - Diabetes, Obesity and Metabolism, 2019 - Wiley Online Library
Sodium glucose co‐transporter 2 inhibitors (SGLT2is) are the first class of glucose lowering
agent to be shown to reduce cardiovascular events. They are generally well tolerated with …

Safety of sodium-glucose co-transporter 2 inhibitors

JB McGill, S Subramanian - The American Journal of Medicine, 2019 - Elsevier
Abstract Sodium-glucose co-transporter 2 (SGLT2) inhibitors have a well-defined safety
profile based on data obtained from numerous clinical trials, including cardiovascular …

Benefits and harms of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes: a systematic review and meta-analysis

H Storgaard, LL Gluud, C Bennett, MF Grøndahl… - PloS one, 2016 - journals.plos.org
Objective Sodium-glucose co-transporter 2 inhibitors (SGLT2-i) are a novel drug class for
the treatment of diabetes. We aimed at describing the maximal benefits and risks associated …

Sodium-glucose co-transporter 2 inhibitors and cardiovascular outcomes: a systematic review and meta-analysis

MS Usman, TJ Siddiqi, MM Memon… - European journal of …, 2018 - journals.sagepub.com
Background The risks and benefits of sodium-glucose co-transporter 2 (SGLT2) inhibitors on
cardiovascular outcomes have not been well established. We pooled evidence from all …

Sodium glucose cotransporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study

P Ueda, H Svanström, M Melbye, B Eliasson… - bmj, 2018 - bmj.com
Objective To assess the association between the use of sodium glucose cotransporter 2
(SGLT2) inhibitors and seven serious adverse events of current concern. Design Register …

Net effects of sodium-glucose co-transporter-2 inhibition in different patient groups: a meta-analysis of large placebo-controlled randomized trials

N Staplin, AJ Roddick, J Emberson, C Reith… - …, 2021 - thelancet.com
Background The net absolute effects of sodium-glucose co-transporter-2 (SGLT-2) inhibitors
across different patient groups have not been quantified. Methods We performed a meta …

Risks associated with SGLT2 inhibitors: an overview

M Singh, A Kumar - Current drug safety, 2018 - ingentaconnect.com
Background: Sodium glucose co-transport 2 inhibitors (SGLT2-i) are the new class of
antidiabetic medications which are recently approved (2013) by the Food and Drug …