Therapeutic approaches to Alzheimer's disease

HW Klafki, M Staufenbiel, J Kornhuber, J Wiltfang - Brain, 2006 - academic.oup.com
Alzheimer's disease is an age-related progressive neurodegenerative disorder with an
enormous unmet medical need. It is the most common form of dementia affecting∼ 5% of …

Current advances in the treatment of Alzheimer's disease: focused on considerations targeting Aβ and tau

Y Hong-Qi, S Zhi-Kun, C Sheng-Di - Translational neurodegeneration, 2012 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mainly the memory
and cognitive function in elderly. Extracellular beta amyloid deposition and intracellular tau …

Recent therapeutic strategies targeting beta amyloid and tauopathies in Alzheimer's disease

Y Madav, S Wairkar, B Prabhakar - Brain research bulletin, 2019 - Elsevier
Alzheimer's disease (AD) has been a global concern for years due to its severe implications
that affects the quality of life of the patients. The available line of therapy for treating …

Therapeutics of Alzheimer's disease: Past, present and future

R Anand, KD Gill, AA Mahdi - Neuropharmacology, 2014 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

Current perspectives on pharmacotherapy of Alzheimer's disease

K Chopra, S Misra, A Kuhad - Expert opinion on pharmacotherapy, 2011 - Taylor & Francis
Introduction: Alzheimer's disease (AD) is a daunting public health threat that has prompted
the scientific community's ongoing efforts to decipher the underlying disease mechanism …

Current therapeutic targets for the treatment of Alzheimer's disease

JD Grill, JL Cummings - Expert review of neurotherapeutics, 2010 - Taylor & Francis
Alzheimer's disease is a progressive neurodegenerative disease for which no cure exists.
There is a substantial need for new therapies that offer improved symptomatic benefit and …

Current drug targets for Alzheimer's disease treatment

DK Lahiri, MR Farlow, NH Greig… - Drug development …, 2002 - Wiley Online Library
Abstract Alzheimer's disease (AD), the most common form of dementia among the elderly, is
a progressive, degenerative disorder of the brain with a loss of memory and cognition. A …

Recent developments in Alzheimer's disease therapeutics

MS Rafii, PS Aisen - BMC medicine, 2009 - Springer
Alzheimer's disease is a devastating neurological disorder that affects more than 37 million
people worldwide. The economic burden of Alzheimer's disease is massive; in the United …

Advances in the therapy of Alzheimer's disease: targeting amyloid beta and tau and perspectives for the future

H Hampel, LS Schneider, E Giacobini… - Expert review of …, 2015 - Taylor & Francis
Worldwide multidisciplinary translational research has led to a growing knowledge of the
genetics and molecular pathogenesis of Alzheimer's disease (AD) indicating that …

Novel insights for the treatment of Alzheimer's disease

A Kurz, R Perneczky - Progress in Neuro-Psychopharmacology and …, 2011 - Elsevier
The development of treatments for Alzheimer's disease (AD) is currently shifting away from
the correction of neurotransmitter abnormalities and from attempts to remove the …