Efficacy and safety of lacidipine, a new long-lasting calcium antagonist, in elderly hypertensive patients

P Rizzini, C Castello, S Salvi… - Journal of cardiovascular …, 1991 - journals.lww.com
Elderly patients are becoming a greater proportion of the hypertensive population. In
addition, they may respond differently to drugs, both pharmacodynam-ically and …

Benefits of antihypertensive drug treatment in elderly patients with isolated systolic hypertension

JG Wang, JA Staessen - The Netherlands Journal of Medicine, 2001 - Elsevier
Isolated systolic hypertension affects over 15% of all people older than 60 years. In the
elderly, systolic hypertension is a major modifiable cardiovascular risk factor. Systolic blood …

Why is antihypertensive drug therapy needed in elderly patients with systolodiastolic hypertension?

L Thijs, R Fagard, P Lijnen, J Staessen… - … : Official Journal of the …, 1994 - europepmc.org
Objective This paper presents a meta-analysis of eight outcome trials of antihypertensive
drug treatment in elderly hypertensive patients, and uses the results of these trials to discuss …

Trials in isolated systolic hypertension: an update

B Waeber - Current hypertension reports, 2003 - Springer
Isolated systolic hypertension (ISH) has proved to be a powerful predisposing factor for
cardiovascular diseases in the elderly. Recent placebo-controlled interventional trials such …

Treatment strategies for isolated systolic hypertension in elderly patients

F Angeli, P Verdecchia, S Masnaghetti… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Hypertension is a major and modifiable risk factor for cardiovascular disease. Its
prevalence is rising as the result of population aging. Isolated systolic hypertension mostly …

Overview of the outcome trials in older patients with isolated systolic hypertension

JA Staessen, JG Wang, L Thijs, R Fagard - Journal of human …, 1999 - nature.com
Aims: Isolated systolic hypertension affects over 8 to 15% of all subjects older than 60 years.
In the elderly, systolic hypertension is the major modifiable cardiovascular risk factor. Three …

Isolated systolic hypertension: a new challenge in medicine

TA Sulbaran, ER Silva, G Maestre - Journal of human hypertension, 2002 - nature.com
In the elderly, isolated systolic hypertension (ISH) is a particularly good predictor of
subsequent cardiovascular events. The purpose of this article is to review the evidence …

Optimal drug treatment of systolic hypertension in the elderly

G Pannarale - Drugs & aging, 2008 - Springer
Approximately two-thirds of the elderly population has hypertension, mainly of the isolated
systolic hypertension (ISH) type. However, while large-scale, randomized controlled …

Hypertension as a function of age

GF Gensini, F Corradi - Italian Heart Journal: Official Journal of the …, 2000 - europepmc.org
Hypertension is one of the main risk factors for cerebrovascular disease (stroke), coronary
artery disease (acute myocardial infarction), congestive heart failure (both systolic and …

Isolated systolic hypertension in the elderly: new insights.

P Palatini, GR Graniero - Clinical and Experimental Hypertension …, 1993 - europepmc.org
Isolated Systolic Hypertension (ISH) is associated with a several-fold excess risk of mortality
from myocardial infarction, stroke and cardiac failure. Decreased compliance of large …