Opinion statement Isolated systolic hypertension (ISH) is the predominant form of
hypertension in persons older than 50 years, who represent the majority of individuals with …

Background In 1989, the European Working Party on High Blood Pressure in the Elderly
started the double-blind, placebo-controlled, Systolic Hypertension in Europe Trial to test the …

BACKGROUND: It has been shown that administration of lacidipine markedly reduces
systolic blood pressure in elderly patients with hypertension without increasing the …

Isolated systolic hypertension affects over 15% of all people older than 60 years of age. In
the elderly, systolic hypertension is a major modifiable cardiovascular risk factor. Systolic …

ISH is a distinct pathogenetic entity defined by SBP readings of greater than or equal to 160
and DBP less than 90 mmHg. The etiology, although not well understood, is in some manner …

Summary Abstract Lacidipine (Caldine®, Lacimen®, Lacipil®, Midotens®, Motens®) is a
once-daily, orally-administered, lipophilic dihydropyridine calcium antagonist with an …

Objective The prevalence of isolated systolic hypertension (ISH) is high in the elderly, and
the objective of this study was to compare the antihypertensive efficacy of olmesartan …

Context In the Systolic Hypertension in the Elderly Program (SHEP) trial, conducted between
1985 and 1990, antihypertensive therapy with chlorthalidone-based stepped-care therapy …

Isolated systolic hypertension affects between 10 and 20'; of the elderly population and
carries a substantial risk of cardiovascular complications. As no prospective, randomized …

Isolated systolic hypertension (ISH) is a common disorder in the elderly, carrying with it a
high risk of cardiovascular morbidity and mortality. Environmental and age-related factors …