Objective: To perform a subgroup analysis on those patients in STOP‐Hypertension‐2 who
had isolated systolic hypertension. Design and methods: The STOP‐Hypertension‐2 study …

Background and objective This interim report from the Syst-Eur trial investigated the level of
blood pressure control achieved during the double-blind period in patients followed in …

Background: Indirect renin-angiotensin blockade by ACE-inhibition has shown to be
effective in lowering blood pressure (BP) in the elderly hypertensive patient. In contrast, the …

Abstract A 90‐day, multicenter, randomized, double‐blind, parallel‐group study was
conducted to compare the efficacy of amlodipine (once a day) with nicardipine (two to three …

Background: Irrespective of their clinical relevance, side effects cannot be considered a
negligible problem in antihypertensive therapy. The aim of this trial was to evaluate the …

Isolated systolic hypertension (ISH) is generally defined as a systolic pressure of 160 mm Hg
or more, with a diastolic pressure cutoff point below 95 mm Hg in some studies and 90 mm …

Background Although present guidelines suggest that treatment of hypertension is more
effective in patients with multiple risk factors and higher risk of cardiovascular events, this …

SHEP-Pilot Study, a randomized, double-blind, placebo-controlled trial of drug therapy for
isolated systolic hypertension, followed 551 participants aged 60 years or more with …

The efficacy and safety of sustained-release diltiazem, 200–300 mg once daily was
compared with that of captopril, 12.5–25 mg twice-daily, in 100 elderly patients (65–85 years …