During normal aging, systolic blood pressure (SBP) rises and a large proportion of elderly
people develop isolated systolic hypertension (ISH). ISH was previously considered to be a …

Event rates in relation to the number of elderly hypertensives treated were calculated from
randomized analysis data from the 840 patients who completed the European Working Party …

This randomised, double-blind, double-dummy, parallel group, multicentre study compared
the efficacy and tolerability of lercanidipine with lacidipine. Elderly patients with isolated …

Isolated systolic hypertension occurs with increased prevalence in the elderly population. It
is characterized by reduced vascular compliance, often combined with increased peripheral …

Background Isolated systolic hyprtension occurs in around 8% of Chinese people aged 60
years or older. In 1988, the Systolic Hypertension in China (Syst-China) Collaborative Group …

The antihypertensive efficacy and safety of amlodipine (5-10 mg once daily for 10 weeks)
was assessed in elderly patients with primary systolic hypertension (average sitting and …

Background: Some antihypertensive therapies are limited by dose-dependent adverse
effects (AEs). The angiotensin II receptor blocker valsartan has been shown to reduce blood …

The effect of atenolol and reserpine on incidence of strokes, coronary heart disease (CHD),
cardiovascular disease (CVD), and mortality was assessed in 4736 persons aged 60 years …

The Systolic Hypertension in the Elderly Program (SHEP) was a double-blind placebo-
controlled outcome trial on the treatment of isolated systolic hypertension (systolic pressure …

Systolic hypertension is a major public health issue in the elderly and is often under-
recognized and under-treated. The concept that systolic blood pressure increases with age …