Crossover comparison of atenolol, enalapril, hydrochlorothiazide and isradipine for isolated systolic systemic hypertension

CA Silagy, JJ McNeil, BP McGrath - The American journal of cardiology, 1992 - Elsevier
The benefit of antihypertensive therapy in reducing cardiovascular morbidity and mortality
associated with isolated systolic hypertension has now been established by the Systolic …

Long-term effects of amlodipine and lisinopril on left ventricular mass and diastolic function in elderly, previously untreated hypertensive patients: the ELVERA trial

WF Terpstra, JF May, AJ Smit, PA de Graeff… - Journal of …, 2001 - journals.lww.com
Objective To compare the effects of a calcium antagonist (amlodipine) and an angiotensin
converting enzyme inhibitor (lisinopril) on left ventricular mass and diastolic function in …

Factors influencing the systolic blood pressure response to drug therapy

C Campo, J Segura, LM Ruilope - The Journal of Clinical …, 2002 - Wiley Online Library
In the early stage of hypertension, diastolic blood pressure has greater prognostic
importance, but in the elderly, systolic blood pressure is the most important marker of …

Systolic Hypertension in Europe (Syst-Eur) trial phase 2: objectives, protocol, and initial progress

J Gasowski, JA Staessen, H Celis, RH Fagard… - Journal of human …, 1999 - nature.com
Abstract The Systolic Hypertension in Europe (Syst-Eur) trial proved that blood pressure
(BP) lowering therapy starting with nitrendipine reduces the risk of cardiovascular …

[引用][C] Systolic Hypertension in the Elderly Program (SHEP) The First Three Months

SB Hulley, D Feigal, C Ireland… - Journal of the …, 1986 - Wiley Online Library
BACKGROUND Diastolic hypertension is a highly prevalent condition and a strong risk
factor for cardiovascular disease; randomized clinical trials have shown that treatment …

Multicenter comparison of once‐and twice‐daily isradipine to hydrochlorothiazide for the treatment of hypertension in elderly patients

JL Holtzman, A Abrams, R Cutler… - Clinical …, 1990 - Wiley Online Library
After 8 weeks of isradipine, a twice‐a‐day dihydropyridine calcium channel blocker, 49% of
elderly patients showed a complete response (sitting diastolic blood presssure≤ 85 mm Hg) …

Long-term lipid profiles with isradipine and hydrochlorothiazide treatment in elderly hypertensive patients

GH Stein, K Matthews, RE Bannatyne… - Journal of …, 1990 - journals.lww.com
Lipid profiles were determined in 56 elderly patients with benign essential hypertension
during an open-label 1-year study of the safety and efficacy of isradipine, a new calcium …

Effects of antihypertensive therapy with lacidipine on ambulatory blood pressure in the elderly.

M Zito, G Abate, C Cervone, L Squassante… - … : Official Journal of the …, 1991 - europepmc.org
Recent multicenter trials have demonstrated that, in hypertensive elderly people, blood
pressure control can significantly decrease the rate of cardiovascular and cerebrovascular …

Epidemiology of hypertension in the elderly

N Morgenstern, RL Byyny - Drugs & Aging, 1992 - Springer
Epidemiological studies confirm that hypertension, particularly systolic hypertension, is a
major cardiovascular and cerebrovascular risk factor in the elderly. Clinical trials …

Hypertension in the elderly

G Pinna, C Pascale, M La Regina, F Orlandini - Italian Journal of Medicine, 2012 - Elsevier
INTRODUCTION: There is a high prevalence of hypertension in the elderly, as evidenced by
clinical and health behavioral policies. Still, there are uncertainties on the treatment of …