[HTML][HTML] PMA treated THP-1-derived-IL-6 promotes EMT of SW48 through STAT3/ERK-dependent activation of Wnt/β-catenin signaling pathway

S Gao, J Hu, X Wu, Z Liang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Colon cancer is one of the most common digestive malignant tumors that leads to high
mortality worldwide, and metastasis is the primary cause of cancer-related death. It is well …

[HTML][HTML] IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer Corrigendum in/10.3892/mmr. 2019.9942

Y Guo, Y Zang, L Lv, F Cai, T Qian… - Molecular …, 2017 - spandidos-publications.com
Abstract Interleukin-8 (IL-8) possesses tumorigenic and proangiogenic properties, and is
overexpressed in many human cancer types. However, only few studies have demonstrated …

[PDF][PDF] MicroRNA-328-3p inhibits the tumorigenesis of bladder cancer through targeting ITGA5 and inactivating PI3K/AKT pathway.

T Yan, XX Ye - European Review for Medical & …, 2019 - europeanreview.org
OBJECTIVE: Previous studies have shown that microRNA-328-3p (miR-328-3p) is involved
in tumorigenesis of many human cancers. However, the specific function of miR-328-3p …

ILC2-modulated T cell–to-MDSC balance is associated with bladder cancer recurrence

MF Chevalier, S Trabanelli, J Racle… - The Journal of …, 2017 - Am Soc Clin Investig
Non-muscle–invasive bladder cancer (NMIBC) is a highly recurrent tumor despite
intravesical immunotherapy instillation with the bacillus Calmette-Guérin (BCG) vaccine. In a …

Regulatory mechanisms of interleukin‐8 production induced by tumour necrosis factor‐α in human hepatocellular carcinoma cells

Y Wang, W Wang, L Wang, X Wang… - Journal of cellular and …, 2012 - Wiley Online Library
Abstract Interleukin (IL)‐8 plays the critical role in the initiation of micro‐environmental
inflammation responsible for tumour growth and patient prognosis. This study aimed at …

Cigarette smoke extract-induced proliferation of normal human urothelial cells via the MAPK/AP‑1 pathway

H Geng, L Zhao, Z Liang, Z Zhang… - Oncology …, 2017 - spandidos-publications.com
Bladder cancer (BC) is universally acknowledged as a significant public health issue,
worldwide. Numerous studies have demonstrated that cigarette smoke is the primary risk …

IL-17A promotes the migration and invasiveness of cervical cancer cells by coordinately activating MMPs expression via the p38/NF-κB signal pathway

M Feng, Y Wang, K Chen, Z Bian, J Wu, Q Gao - PLoS One, 2014 - journals.plos.org
Objective IL-17A plays an important role in many inflammatory diseases and cancers. We
aimed to examine the effect of IL-17A on the invasion of cervical cancer cells and study its …

IL-10 promotes tumor aggressiveness via upregulation of CIP2A transcription in lung adenocarcinoma

WW Sung, YC Wang, PL Lin, YW Cheng, CY Chen… - Clinical Cancer …, 2013 - AACR
Abstract Purpose: Interleukin-10 (IL-10) determines virus persistent infection and promotes
viral-associated tumor progression via tumor immune escape. However, the role of IL-10 in …

EIF4A3 serves as a prognostic and immunosuppressive microenvironment factor and inhibits cell apoptosis in bladder cancer

B Hu, R Chen, M Jiang, S Xiong, X Liu, B Fu - PeerJ, 2023 - peerj.com
EIF4A3 (Eukaryotic translation initiation factor 4A3 (EIF4A3) was recently recognized as an
oncogene; however, its role in BLCA (bladder cancer) remains unclear. We explored EIF4A3 …

Interleukin-6: a critical cytokine in cancer multidrug resistance

M Ghandadi, A Sahebkar - Current pharmaceutical design, 2016 - ingentaconnect.com
Multidrug resistance (MDR) is a phenomenon through which tumor cells develop resistance
against the cytotoxic effects of various structurally and mechanistically unrelated …