Interferon gamma-1b in the treatment of idiopathic pulmonary fibrosis

MA Pacanowski, GW Amsden - Annals of Pharmacotherapy, 2005 - journals.sagepub.com
Objective: To examine the clinical aspects of idiopathic pulmonary fibrosis (IPF) and the
efficacy and safety of interferon gamma-1b (IFNγ− 1b) in its treatment. Data Sources …

Long-term survival in idiopathic pulmonary fibrosis patients treated with interferon gamma-1b.(Interstitial lung disease: outcomes: 2: 00pm-3: 30pm)

R Ziesche, WZ Bradford, M Crager, LH Block - Chest, 2002 - go.gale.com
PURPOSE: Idiopathic Pulmonary Fibrosis (IPF) is characterized by progressive respiratory
insufficiency and a median survival of only 2-5 years. There is no therapy for IPF with …

Interferon-γ1b therapy in idiopathic pulmonary fibrosis: a metaanalysis

EK Bajwa, NT Ayas, M Schulzer, E Mak, JH Ryu… - Chest, 2005 - Elsevier
Context Despite the investigation of multiple therapeutic options, idiopathic pulmonary
fibrosis (IPF) remains a devastating, progressively fatal disease. Much interest has focused …

Interferon-γ 1b: impact of new indications (idiopathic pulmonary fibrosis)

AN Aggarwal, D Behera - Expert Opinion on Pharmacotherapy, 2000 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive disease with inadequate
response to conventional treatment with corticosteroids and/or immunosuppressive agents …

[HTML][HTML] A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis

G Raghu, KK Brown, WZ Bradford… - … England Journal of …, 2004 - Mass Medical Soc
Background Idiopathic pulmonary fibrosis is a progressive, fatal disease with no known
efficacious therapy. Methods In a double-blind, multinational trial, we randomly assigned …

Treatment of idiopathic pulmonary fibrosis: is there anything new?

MM Abdelaziz, YS Samman, SO Wali… - …, 2005 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic fibrosing interstitial
pneumonia of unknown aetiology and is associated with the histological picture of usual …

Interferon gamma-1b as therapy for idiopathic pulmonary fibrosis: an intrapatient analysis

SD Nathan, SD Barnett, B Moran, DL Helman… - Respiration, 2004 - karger.com
Background: The only proven therapeutic option for idiopathic pulmonary fibrosis (IPF) is
lung transplantation. It is biologically plausible that interferon gamma-1b (G-IFN) may halt or …

Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial

TE King, C Albera, WZ Bradford, U Costabel, P Hormel… - The Lancet, 2009 - thelancet.com
Background Idiopathic pulmonary fibrosis is a fatal disease for which no effective treatment
exists. We assessed whether treatment with interferon gamma-1b improved survival …

Does interferon‐γ improve pulmonary function in idiopathic pulmonary fibrosis?

A Prasse, KM Müller, C Kurz, H Hamm… - European Respiratory …, 2003 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a disease with progressive and devastating
deterioration of lung function and a fatal prognosis, despite aggressive therapeutic attempts …

Interferon gamma-1b therapy for advanced idiopathic pulmonary fibrosis

S Kalra, JP Utz, JH Ryu… - Mayo Clinic …, 2003 - Elsevier
OBJECTIVE To report on observations made in a group of patients with idiopathic
pulmonary fibrosis/usual interstitial pneumonia (IPF/UIP) who were treated with interferon …